Construction of a stereocomplex between poly(d-lactide) grafted hydroxyapatite and poly(l-lactide): toward a bioactive composite scaffold with enhanced interfacial bonding

Abstract

Poly (L-lactide) (PLLA)/hydroxyapatite (HAP) composite scaffold is expected to combine the favorable compatibility and processability of PLLA with the excellent bioactivity and osteoconductivity of HAP. Unfortunately, poor interfacial bonding between...

In Situ Growth of a Metal–Organic Framework on Graphene Oxide for the Chemo-Photothermal Therapy of Bacterial Infection in Bone Repair

“…In turn, GO promoted the uniform dispersion of ZIF-8 due to the anchoring effect. Then, ZIF-8@GO was incorporated into a poly- l -lactic acid (PLLA) scaffold fabricated by selective laser sintering (SLS), which was capable of producing bone scaffolds with complex shapes and porous interiors. − The morphology and microstructure of ZIF-8@GO were comprehensively investigated. The overall performance of the scaffolds was studied, including their photothermal performance, antibacterial properties, and cell behavior.…”

Sr2+ Sustained Release System Augments Bioactivity of Polymer Scaffold

“…24 It should be noted that the stretching vibration of CO peak at 1760 cm −1 slightly shifted to a lower wavenumber with the introduction of HA and SrHA, which might be attributed to the formation of hydrogen bonds between the carbonyl groups in PLLA and the methyl groups on the surface of nanoparticles. 36 Selective laser sintering, as a nonconventional thermal processing technique, exploited laser beam to rapidly heat powder materials and drive adjacent powder particles to melt and consolidate together. 37 The instantaneously laser heat might affect the phase structure of the materials and further influence the macro performance of the scaffold.…”

“…Moreover, the peaks at 1035 and 1090 cm –1 belonged to the asymmetric stretching vibrations of PO in PO 4 3– groups . It should be noted that the stretching vibration of CO peak at 1760 cm –1 slightly shifted to a lower wavenumber with the introduction of HA and SrHA, which might be attributed to the formation of hydrogen bonds between the carbonyl groups in PLLA and the methyl groups on the surface of nanoparticles …”

Water-responsive shape memory thermoplastic polyurethane scaffolds triggered at body temperature for bone defect repair

“…The SLS system contained a CO 2 laser generator, a galvanometer scanner and a computer system. 34,65,66 To satisfy the requirement of a 3D scaffold model, a cylindrical model with interconnected pores (j 15 mm  6 mm) was firstly designed and built using the 3D modeling software (Solidworks) and converted to the format of STL, which was imported into the 3DPrinter software and designed the laser processing path then. During the layer-by-layer manufacturing process, the TPU powder was paved evenly as a layer.…”