2015
DOI: 10.1039/c4tb01854k
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Construction of d-α-tocopheryl polyethylene glycol succinate/PEO core–shell nanofibers on a blood-contacting surface to reduce the hemolysis of preserved erythrocytes

Abstract: The TPGS released from the electrospun SEBS protected the preserved red blood cells from oxidative damage, resulting in low hemolysis and mechanical fragility.

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Cited by 13 publications
(8 citation statements)
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“…Controlled release of lecithin and D-a-tocopheryl polyethylene glycol 1000 succinate on the surface of SEBS have been reported to reduce the hemolysis of RBC substantially. 18,19 However, the release of biomolecules is not responsive to physiological changes in the medium and early release may disturb the metabolism and normal function of the cells. Recently, crown ether-based copolymers have been synthesized for rapid K + -triggered drug release.…”
Section: Introductionmentioning
confidence: 99%
“…Controlled release of lecithin and D-a-tocopheryl polyethylene glycol 1000 succinate on the surface of SEBS have been reported to reduce the hemolysis of RBC substantially. 18,19 However, the release of biomolecules is not responsive to physiological changes in the medium and early release may disturb the metabolism and normal function of the cells. Recently, crown ether-based copolymers have been synthesized for rapid K + -triggered drug release.…”
Section: Introductionmentioning
confidence: 99%
“…6 Based on the above rationale, much effort (such as copolymerization, blending and compositing) has been made to modify PBSu. 7 On account of its excellent mechanical properties and good biodegradability, various reports suggested the use of PBSu-based random or block copolymers as green materials. 8 Blending PBSu with poly(lactic acid) (PLA), poly(hydroxybutyrate) (PHB) or natural polymers, such as chitosan and silk fiber, has also been widely investigated.…”
Section: Introductionmentioning
confidence: 99%
“…The antioxidant and antihemolytic properties of TPGS have been confirmed by various studies. 6,56 Fig. 6 shows the hemolysis rates of PP-g-P (NIPAAm) and PP-g-P (NIPAAm-co-APMA) with different M NIPAAm:APMA and their corresponding Ag NP-loaded surfaces at different time points.…”
Section: Adsorption Of Ag Nps On a Grafted Pp Surfacementioning
confidence: 99%