Consumption and foraging behaviors for common stimulants (nicotine, caffeine)

Phillips, James G.; Currie, Jonathan; Ogeil, Rowan P.

doi:10.1080/10550887.2015.1094721

Cited by 8 publications

(12 citation statements)

References 59 publications

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“…Our overarching goal for the current study was to test whether an experiential foraging task can measure addiction-relevant behaviors, following from theories that conceptualize risky substance use within foraging models (14). More specifically, we aimed to determine 1) whether subjects showed differential responses to risky losses with respect to their enjoyment of reward and acceptance of subsequent risky deals, and 2) whether individual differences in response to risky losses predicted variation in trait-level externalizing, a risk factor for substance use disorders (15–17).…”

Section: Introductionmentioning

confidence: 99%

Learning From Loss After Risk: Dissociating Reward Pursuit and Reward Valuation in a Naturalistic Foraging Task

2019

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A fundamental feature of addiction is continued use despite high-cost losses. One possible driver of this feature is a dissociation between reward pursuit and reward valuation. To test for this dissociation, we employed a foraging paradigm with real-time delays and video rewards. Subjects made stay/skip choices on risky and non-risky offers; risky losses were operationalized as receipt of the longer delay after accepting a risky deal. We found that reward likability following risky losses predicted reward pursuit (i.e., subsequent choices), while there was no effect on reward valuation or reward pursuit in the absence of such losses. Individuals with high trait externalizing, who may be vulnerable to addiction, showed a dissociation between these phenomena: they liked videos more after risky losses but showed no decrease in choosing to stay on subsequent risky offers. This suggests that the inability to learn from mistakes is a potential component of risk for addiction.

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Section: Introductionmentioning

confidence: 99%

Learning From Loss After Risk: Dissociating Reward Pursuit and Reward Valuation in a Naturalistic Foraging Task

2019

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“…During our three-month experiment, the rats ingesting white tea showed greater fluid intake than the rats ingesting water (P < 0.0001). This increase in fluid consumption may be due to the presence of caffeine in white tea; caffeine can generate dependency when ingested frequently (Phillips et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

White tea intake interferes with the expression of angiogenic factors in the corpora lutea of superovulated rats

Santos

Freire

Vieira

et al. 2018

Int J of Food Sci Tech

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Summary White tea derived from the Camellia sinensis (L.) plant has anticancer effects. Its main catechin decreases the gene expression of Vegf in tumours. However, VEGF is also the angiogenic factor of the reproductive organs. In this study, Wistar rats were divided into the following groups (n = 30): the control group (CT), which received water, and the white tea intake group (WT), for 3 months. At the end of every month, the corpora lutea (CL) of ten rats were removed to evaluate the gene expression of Vegf and its receptors (Flt‐1 and Kdr). White tea increased the relative mRNA abundance of Vegf (CT = 0.95 ± 0.06 and WT = 2.13 ± 0.19), Kdr (CT = 0.88 ± 0.06 and WT = 1.94 ± 0.32) and Flt‐1 (CT = 0.94 ± 0.06 and WT = 2.11 ± 0.22) in CL (P < 0.05). White tea increased angiogenic‐related genes in rat CL but did not alter the number of rat CL.

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“…Hence, this polyelectrolyte complexes has usually been used to control drug release [31][32][33][34]. In this study, caffeine was used as a release drug owing to its cheap, harmless, convenient and productive medicine for pharmacotherapy [35][36][37][38].…”

Section: Introductionmentioning

confidence: 99%

Chitosan/ Alginate /Gellan Gum Hybrid Hydrogel as a Vehicle for Controlled Release of Drug

Pan¹

2019

IJBMR

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Hybrid hydrogel was fabricated by a classic sol-gel method using EDC/NHS as crosslink reagent grafting onto the thermoplastic polyurethane (TPU), nonwoven fabric, for controlled release of drug. In this study, precursor acetic acid (AA) was used to plasma deposit on the surface of TPU to form a hydrophilic thin film. Hybrid hydrogel was investigated through scanning electron microscopy (SEM), water contact angle (WCA) measurement, Fourier transform infra-red (FTIR) spectroscopy, UV/V is spectroscopy, equilibrium swelling ratio, MTT assay and drug delivery system studies. This polyelectrolyte complexes (PECs) formed hydrogel, pH-sensitive type, was evaluated at pH value of 1.2 and 7.4 of buffer solution and at temperature of 37°C to observe its rate of swelling and drug release features with caffeine. Moreover, the mechanism of caffeine release from membrane devices (n=0.58) are anomalous transport, non-Fickian diffusion, the value of n lies between 0.43 and 0.85. It has an excellent release ratio up to about 90% absorption cumulative amounts of caffeine at pH 7.4 after 8h and could be a beneficial carrier for fragile drugs.

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Consumption and foraging behaviors for common stimulants (nicotine, caffeine)

Cited by 8 publications

References 59 publications

Learning From Loss After Risk: Dissociating Reward Pursuit and Reward Valuation in a Naturalistic Foraging Task

Learning From Loss After Risk: Dissociating Reward Pursuit and Reward Valuation in a Naturalistic Foraging Task

White tea intake interferes with the expression of angiogenic factors in the corpora lutea of superovulated rats

Chitosan/ Alginate /Gellan Gum Hybrid Hydrogel as a Vehicle for Controlled Release of Drug

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