The aim of this paper is to identify preferred Central and Eastern Europe (CEE) medical tourism destinations (MTD) and medical services in the context of socio-demographic determinants. The computer-assisted web interviewing (CAWI) method was used. A total of 282 completed self-administered questionnaires were collected from Britons and Germans, who constitute a large segment of medical tourists in CEE. Subsequently, the responses were analysed using the chi-square test and the method of logistic regression function. The results indicated that the chosen destinations and medical services vary depending on gender, age and nationality. The survey results have implications for scholars, allowing them to understand the way Britons and Germans evaluate MTDs and medical services in CEE, as well as for medical tourism facilitators/brokers and destination management organisations engaged in the process of creating a medical tourism product. The obtained results have also implications for further research related to the development of medical tourism in CEE.