Contact sensitivity to nickel and other metals in jewelry reactors

Gawkrodger, David J.; Lewis, Fiona M.; Shah, Manu

doi:10.1067/mjd.2000.107235

Cited by 54 publications

(52 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Allergies to palladium [8,9] and to gold, cobalt and copper [9] usually accompany nickel salt allergies. Previously, allergic reactions in the oral cavity to chromium alloys or in patients with metal restorations were thought to be exceptionally rare [10], but in recent years the number of patients with diagnosed dermal allergies to the most commonly used metal alloy components has grown rapidly [3,4,[11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

“…In particular, ingredients of NiCr and CoCr alloys such as nickel, cobalt, chromium, and molybdenum, exhibit strong effects on the body cells and tissues and elicit toxic and morphological effects as well as cellular metabolic disorders [2][3][4][5][6][7][8]. On the other hand, allergic reactions to metals such as Ni, Cr, Co, Pd, Au, Cu and Ag found in restorative materials vary depending on gender [3] and profession [4].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cytological response of palatal epithelium to TiN-coated CoCr alloy denture

Łukomska−Szymańska

Brzeziński

Zieliński

et al. 2012

Folia Histochem Cytobiol.

View full text Add to dashboard Cite

Abstract:The aim of this study was to assess the impact of titanium nitride coatings on CoCr alloy metal parts in framework dentures on human palatal epithelium cytology compared to framework dentures made with the same alloy but without titanium nitride coating, and to acrylic dentures. Every prosthetic restoration introduced into the oral cavity and remaining in direct contact with the palate exhibits a varied and harmful effect on the state of the palatal epithelium by disturbing its keratinization. CoCr alloy dentures produce a significantly greater perturbation of keratinization compared to acrylic dentures. There is no evidence showing that a titanium nitride coating of the CoCr alloy plays a protective role in the environment of the oral cavity.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cytological response of palatal epithelium to TiN-coated CoCr alloy denture

Łukomska−Szymańska

Brzeziński

Zieliński

et al. 2012

Folia Histochem Cytobiol.

View full text Add to dashboard Cite

show abstract

“…Destas, 15 (44,1%) não apresentaram reação aos metais testados. Dado semelhante ao encontrado por Gawkrodger et al, quando observaram que em 449 indivíduos com história de reação a bijuterias, 50% apresentavam negatividade no teste de contato, sem diferença significante de atopia entre os grupos com teste de contato negativo e aqueles com teste positivo 24 . Ocasionalmente uma pessoa pode ter uma alergia verdadeira, mas mostrar uma resposta negativa ao teste de contato 19 .…”

Section: Discussionunclassified

“…Ocasionalmente uma pessoa pode ter uma alergia verdadeira, mas mostrar uma resposta negativa ao teste de contato 19 . Outras explicações possíveis seriam reação cutânea irritante ou alergia a outros metais, como o paládio 24 .…”

Section: Discussionunclassified

Ear piercing as a risk factor for contact allergy to nickel

Brandão

Girundi²,

Castro³

2010

J Pediatr (Rio J)

View full text Add to dashboard Cite

Objectives: To determine the prevalence of metal contact allergy among the children seen at a health center and to characterize children with metal allergies in terms of risk factors. Methods:This was an uncontrolled cross-sectional study undertaken at a health center in Belo Horizonte, Brazil. Children aged from 0 to 12 years were recruited when they presented at the health center for routine pediatric consultations and were given contact tests for chrome, cobalt and nickel. Statistical analyses were conducted on test readings taken at 96 hours. Results classed as weak (+), strong (++) or extreme (+++) were defined as "reaction," while those classed as doubtful, negative or irritant were defined as "no reaction."Results: A total of 144 children completed the study protocol. Of these, 4.9% exhibited a reaction to chrome, 9.7% to cobalt and 20.1% to nickel. Patients with pierced ears were more likely to react to nickel than those without pierced ears (p = 0.031 and odds ratio = 2.8). Conclusions:In view of the current tendency for the prevalence of nickel allergy to increase, parents should be warned about its association with ear piercing. Further studies are needed to determine the ideal age for ear piercing and the ideal materials for earrings. J Pediatr (Rio J). 2010;86(2):149-154:Cobalt, child, chrome, contact dermatitis, hypersensitivity, nickel. ResumoObjetivos: Determinar a prevalência da alergia de contato aos metais em crianças que frequentam um centro de saúde e caracterizar o subgrupo com alergia em relação aos fatores de risco.Métodos: Estudo transversal não controlado, conduzido em um centro de saúde de Belo Horizonte (MG). Foram incluídas crianças com idades entre 0 e 12 anos que se apresentaram para consulta pediátrica de rotina, sendo aplicados testes de contato para o cromo, o cobalto e o níquel. As análises estatísticas foram realizadas com base na leitura do teste em 96 horas. Leituras classificadas como fraca (+), forte (++) ou extrema (+++) foram consideradas como reação, enquanto as classificadas como duvidosa, negativa ou irritativa foram consideradas como não reação. Resultados:Completaram o estudo 144 crianças. Destas, 4,9% apresentaram reação ao cromo, 9,7% ao cobalto e 20,1% ao níquel. Os pacientes com orelha perfurada tiveram mais chance de reação ao níquel do que aqueles sem essa característica (p = 0,031 e odds ratio = 2,8). Conclusões:Em face da tendência atual ao aumento da alergia ao níquel, familiares devem ser alertados sobre a sua associação com a perfuração das orelhas. Estudos posteriores são necessários para avaliar a idade ideal para a perfuração das orelhas e o material ideal para brincos. J Pediatr (Rio J) IntroduçãoVários estudos mostram os metais como os sensibilizantes de contato mais comuns em crianças, principalmente o níquel [1][2][3][4] . Dados recentes vêm revelando aumento na taxa de alergia a esse metal em países industrializados 5 .A influência do modismo e do estilo de vida tem importante papel no desenvolvimento dessa sensibilização. A dermatite de ...

show abstract

“…Metals in direct contact with the skin can lead to contact dermatitis [7][8][9] , while corrosion products of dental alloys in the oral cavity and gastrointestinal tract can give rise to local reactions [10][11][12] .…”

Section: Introductionmentioning

confidence: 99%

Metallic Pigmentation of Human Teeth and Gingiva: Morphological and Immunological Aspects

et al. 2007

View full text Add to dashboard Cite

The composition of metallic pigmentations in gingiva and dental roots was determined by means of transmission electron microscopy with energy dispersive x-ray microanalysis. The systemic immune response to the metals found in the oral cavity was evaluated in 10 patients by using a modified lymphocyte proliferation test. Immunological results were compared with a group of five controls without metallic materials and pigmentation. Dense particles of various shapes and sizes, as well as of diverse extracellular and intracellular localization patterns, were detected in the pigmented lamina propria gingivae. Metallic deposits consisted predominantly of silver accompanied by selenium or sulfur or both. Besides, Ag, Au, Cr, Ni, Fe, Hg, Cu, and Ti were identified in dentinal tubules of teeth reconstructed with dental alloys. Nine patients with metallic pigmentations had a positive lymphocyte proliferative response to one or more metals present in their own metal reconstructions. Results of this study thus indicated that dental alloys-by virtue of their corrosion process-might pose a significant risk to immunologically susceptible patients.

show abstract

Contact sensitivity to nickel and other metals in jewelry reactors

Cited by 54 publications

References 28 publications

Cytological response of palatal epithelium to TiN-coated CoCr alloy denture

Cytological response of palatal epithelium to TiN-coated CoCr alloy denture

Ear piercing as a risk factor for contact allergy to nickel

Metallic Pigmentation of Human Teeth and Gingiva: Morphological and Immunological Aspects

Contact Info

Product

Resources

About