Contact vitiligo appearing after allergic contact dermatitis from aromatic reactive diluents in an epoxy resin system

Silvestre, Juan Francisco; Albares, M.P.; Escutia, B.; Vergara, Gloria; Pascual, José C.; Botella, Rafael

doi:10.1111/j.0105-1873.2003.0128l.x

Cited by 15 publications

(4 citation statements)

References 5 publications

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“…Depigmentation after allergic contact dermatitis due to ERS has already been described (8, 9). However, to our knowledge, this is the first report of contact vitiligo following a positive patch test reaction to TGPAP, suggesting a strong sensitizing potential and pointing to a rare adverse event of patch testing in general.…”

Section: Discussionmentioning

confidence: 88%

Contact vitiligo following a strong patch test reaction to triglycidyl‐p‐aminophenol in an aircraft industry worker: case report and review of the literature

2005

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Epoxy resin systems (ERSs) are a frequent cause of occupational allergic contact dermatitis. A 50-year-old patient developed eczematous skin lesions on the back of his hands, lower arms and eye lids, 2 months after he had started working in aircraft construction. Patch tests showed positive reactions at day 3 to nickel sulfate, epoxy resin based on diglycidyl ether of bisphenol F (DGEBF) and 1,4-butanediol diglycidyl ether (1,4-BDDGE). The chemical triglycidyl-p-aminophenol (TGPAP) applied at 1% and 0.1% induced the strongest (+++ positive) reaction. About 4 months after the patch test with TGPAP, the patient presented with 2 circular depigmented spots in the former TGPAP-patch test areas. Dermatohistopathology confirmed the diagnosis of contact vitiligo.

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Section: Discussionmentioning

confidence: 88%

Contact vitiligo following a strong patch test reaction to triglycidyl‐p‐aminophenol in an aircraft industry worker: case report and review of the literature

2005

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“…For chemical provoking factors, seven categories were differentiated: bleaching agents (I), pesticides (II), rubber (III), petroleum (IV), glue (V), photochemicals (VI) and solvents (VII). These chemicals are suspect provoking factors for vitiligo 7–10,16–22 . If required, patients could indicate other factors (category VIII).…”

Section: Methodsmentioning

confidence: 99%

Provoking factors, including chemicals, in Dutch patients with vitiligo

et al. 2013

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“…Phenolic/catechol derivatives are major chemicals known to be associated with vitiligo, and could induce the condition8,11,12,13,14. A variety of allergens that cause allergic contact dermatitis (ACD) might also be initiating factors of contact/occupational vitiligo15,16,17,18,19,20. However, the frequency of vitiligo occurrence in patients of particular occupations, and the associated environmental and occupational exposures have not yet been reported.…”

Section: Introductionmentioning

confidence: 99%

A Multicenter Collaborative Study by the Korean Society of Vitiligo about Patients' Occupations and the Provoking Factors of Vitiligo

et al. 2014

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BackgroundIt was previously thought that persons with genetic predispositions to vitiligo develop the condition after exposure to various precipitating environmental factors. However, in many cases, the aggravating factors of vitiligo have not been clearly identified.ObjectiveTo identify the aggravating factors of vitiligo in the working environment and daily life.MethodsA total of 489 vitiligo patients were recruited from 10 institutions in South Korea; patients were provided with a questionnaire about environmental factors and behavior patterns in the workplace and in daily life, and their association with vitiligo.ResultsNinety-five of the 470 enrolled patients (20.2%) answered that environmental risk factors in daily life and in the workplace affected the development of vitiligo. The most frequently attributed causes were trauma and burn (13.6%), followed by sunlight (12.8%), stress (12.8%), cleaning products/disinfectant/chemicals (4.9%), and hair dye (2.1%).ConclusionVitiligo of the hand and foot was associated with frequent exposure to aggravating materials and overexposure to sunlight, along with frequent trauma of these areas, all of which could be considered important risk factors of vitiligo. The development of vitiligo could potentially be controlled through the early detection of aggravating factors.

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Contact vitiligo appearing after allergic contact dermatitis from aromatic reactive diluents in an epoxy resin system

Cited by 15 publications

References 5 publications

Contact vitiligo following a strong patch test reaction to triglycidyl‐p‐aminophenol in an aircraft industry worker: case report and review of the literature

Contact vitiligo following a strong patch test reaction to triglycidyl‐p‐aminophenol in an aircraft industry worker: case report and review of the literature

Provoking factors, including chemicals, in Dutch patients with vitiligo

A Multicenter Collaborative Study by the Korean Society of Vitiligo about Patients' Occupations and the Provoking Factors of Vitiligo

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