Content, Composition, and Metabolism of Mammalian and Avian Lipids That Contain Ether Groups

Horrocks, Lloyd A.

doi:10.1016/b978-0-12-654150-2.50016-6

Cited by 118 publications

(68 citation statements)

References 348 publications

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“…these values compare well with published values (34). These data confirmed our Western blot results on the enrichment of the phospholipid fractions and showed that these isolated phospholipids lacked significant PUFA losses attributable to postmortem hydrolysis.…”

Section: Quantification Of F 2 -Dihomo-isops Esterified To Phospholipsupporting

confidence: 81%

F2-Dihomo-isoprostanes arise from free radical attack on adrenic acid

VanRollins

Woltjer

Yin

et al. 2008

Journal of Lipid Research

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Unlike F 4 -neuroprostanes (F 4 -NeuroPs), which are relatively selective in vivo markers of oxidative damage to neuronal membranes, there currently is no method to assess the extent of free radical damage to myelin with relative selectively. The polyunsaturated fatty acid adrenic acid (AdA) is susceptible to free radical attack and, at least in primates, is concentrated in myelin within white matter.

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Section: Quantification Of F 2 -Dihomo-isops Esterified To Phospholipsupporting

confidence: 81%

F2-Dihomo-isoprostanes arise from free radical attack on adrenic acid

VanRollins

Woltjer

Yin

et al. 2008

Journal of Lipid Research

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“…This is understandable as increased levels of fat in muscle tissue are mainly associated with triacylglycerols and not phospholipids, and plasmalogens being phospholipids would thus not be affected. We also considered whether different dietary fatty acids, such as 18:2n-6 and 18:3n-3, could affect the plasmalogenic content in muscle tissue, even though these unsaturated fatty acids are not incorporated into plasmalogenic lipids (Horrocks, 1972;Wolff, 2002). It would appear, however, that increased dietary 18:3n-3 is generally associated with higher levels of plasmalogens, but this should be confirmed by comparing appropriate diets using the same breed.…”

Section: Discussionmentioning

confidence: 99%

Length of concentrate finishing affects the fatty acid composition of grass-fed and genetically lean beef: an emphasis on trans-18:1 and conjugated linoleic acid profiles

Aldai

Dugan

Kramer

et al. 2011

Animal

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Intensively finishing cattle on a high-grain diet is generally used to enhance marbling, whereas extensively finishing on grass is known to provide improved muscle fatty acid profiles. The objective of this study was to evaluate to what extent intensive concentrate finishing (0, 1 or 2 months) can be combined with forage feeding without negatively affecting the fatty acid profile of genetically lean animals. Bulls from the ‘Asturiana de los Valles’ breed were reared under grazing conditions with/without final finishing on a barley-based concentrate: 0 months (control;n= 7), 1 month (n= 10) and 2 months (n= 7). Yearling bulls were slaughtered commercially at an average live weight of 516 ± 9.8 kg. Increasing the finishing time on concentrate significantly increased the saturated and monounsaturated fatty acids, whereas polyunsaturated fatty acids (PUFAs) tended to decrease and it was not possible to increase the long-chain PUFA content in muscle tissue of this breed. An increase was observed for totaltrans-18:1 (average 5.5% with grainv.3.7% for grass). The 11t-18:1/10t-18:1 ratio was significantly higher in grass-fed (average 8.1) compared with grain-finished animals (average 1.1). Grass or limited concentrate finishing reduced the n-6/n-3 ratio in muscle tissue (average 3.6 for 0 and 1 month, and 4.9 for 2 months on grain finishing). The beef was within or close to the recommended values for human consumption (i.e. polyunsaturated/saturated > 0.45, n-6/n-3 < 4.0), and totaltrans-FA content was low. However, finishing increased the content of undesirabletrans-18:1 and conjugated linoleic acid isomers, particularly after 2 months, whereas grass finishing was judged to provide a healthier beef fatty acid profile.

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“…Human blood samples were collected from five healthy volunteers [mean age, 28 Ϯ 11 years; hemoglobin A1c (Hb A1c ), 4.5 Ϯ 0.1%], nine type 2 diabetic patients (mean age, 68 Ϯ 31 years; Hb A1c , 6.9 Ϯ 2.1%), five diabetic patients on chronic hemodialysis (mean age, 76 Ϯ 7 years; Hb A1c , 7.6 Ϯ 3.0%), and five nondia- by guest, on May 11, 2018 www.jlr.org Downloaded from betic patients on chronic hemodialysis (mean age, 65 Ϯ 8 years; Hb A1c , 4.7 Ϯ 0.8%) after informed consent had been obtained. For diabetic patients, their blood sugar was under control (insulin or diet) at the time of blood draw.…”

Section: Blood Samples and Lipid Extractionmentioning

confidence: 99%