Contextualizing the Use of Oncologic Imaging within Treatment Phases: Imaging Trends and Modality Preferences, 2000–2014

Copeland, Thomas E.; Creasman, Jennifer M.; Seidenwurm, David; Franc, Benjamin L.

doi:10.3747/co.24.3216

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…[5] The utilization of testing in general-and high cost, advanced diagnostic imaging such as CT, MRI, and PET in particular-continues to increase in various phases of breast cancer management. [11][12][13] As we, and others, pursue research aimed at quantifying from claims data the use and appropriateness of testing in breast cancer management, the differentiation of testing specifically for cancer recurrence in the breast cancer population over background rates of testing in non-cancer populations will continue to be important. In the absence of a "gold standard" it is reassuring that we found similar, if not identical, rates of additional testing regardless of method adopted.…”

Section: Discussionmentioning

confidence: 99%

Identifying tests related to breast cancer care in claims data

et al. 2019

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To develop a method for calculating rates of testing for breast cancer recurrence in patients who have already undergone initial treatment for breast cancer, we calculated rates in a cohort of Medicare breast cancer patients and an age-matched non-cancer cohort. We first used only tests with claims including diagnosis codes indicating invasive breast cancer and then used all tests regardless of diagnosis code. For each method, we calculated testing rates in the breast cancer cohort above the background rate in the non-cancer population. The two methods provided similar estimates of testing prevalence and frequency, with exception of prevalence of CT.

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Section: Discussionmentioning

confidence: 99%

Identifying tests related to breast cancer care in claims data

et al. 2019

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“…Generally, it has been demonstrated that tumor size in avascular phase is limited to a diameter of 1 to 2 millimeter and tumor cell population is limited [8], however, the tumor growth in absence of mechanical barriers or therapies is extremely progressive during the Mechanisms involved in tumor growth engages complex multicellular dynamics in different spatio-temporal scales including intracellular, intercellular and extracellular scales [9]. Despite the helpful understandings of tumor growth processes obtained by experiments tied up with recent imaging modalities [10,11], it is hard to evaluate all the various multi-scale phenomena occurring during tumor growth in experimental studies. In this context, a multi-scale modeling embedding various spatio-temporal scales involving in tumor growth would make an acceptable sight of such intricate procedure.…”

Section: Introductionmentioning

confidence: 99%

The pivotal role of angiogenesis in a multi-scale modeling of tumor growth exhibiting the avascular and vascular phases

Salavati

Soltani

Amanpour

2018

Microvascular Research

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The mechanisms involved in tumor growth mainly occur at the microenvironment, where the interactions between the intracellular, intercellular and extracellular scales mediate the dynamics of tumor. In this work, we present a multi-scale model of solid tumor dynamics to simulate the avascular and vascular growth as well as tumor-induced angiogenesis. The extracellular and intercellular scales are modeled using partial differential equations and cellular Potts model, respectively. Also, few biochemical and biophysical rules control the dynamics of intracellular level. On the other hand, the growth of melanoma tumors is modeled in an animal in-vivo study to evaluate the simulation. The simulation shows that the model successfully reproduces a completed image of processes involved in tumor growth such as avascular and vascular growth as well as angiogenesis. The model incorporates the phenotypes of cancerous cells including proliferating, quiescent and necrotic cells, as well as endothelial cells during angiogenesis. The results clearly demonstrate the pivotal effect of angiogenesis on the progression of cancerous cells. Also, the model exhibits important events in tumor-induced angiogenesis like anastomosis. Moreover, the computational trend of tumor growth closely follows the observations in the experimental study.

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Contextualizing the Use of Oncologic Imaging within Treatment Phases: Imaging Trends and Modality Preferences, 2000–2014

Abstract: BackgroundIn the present study, we retrospectively evaluated the use of tomographic imaging in adult cancer

Cited by 2 publications

References 14 publications

Identifying tests related to breast cancer care in claims data

Identifying tests related to breast cancer care in claims data

The pivotal role of angiogenesis in a multi-scale modeling of tumor growth exhibiting the avascular and vascular phases

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