“…Moreover, the problem of global warming and environmental pollution has led the mineral processing industry to focus on the use of low-cost, low-energy, and environmentally friendly methods [4,[6][7][8][9][10]. Thus, several investigations have been focused on the operation and optimization of the bioleaching processes for the extraction of metals from low-grade deposits (by heap bioleaching [11,12]), waste (by columns [13,14]), and concentrates (by bioleaching tanks [13,15,16]) which considerably have lower costs and environment effects [11,[16][17][18][19][20][21][22][23][24].…”