Continuous-Flow Left Ventricular Assist Device Thrombosis: A Danger Foreseen is a Danger Avoided

Fatullayev, Javid; Samak, Mostafa; Sabashnikov, Anton; Zeriouh, Mohamed; Rahmanian, Parwis B.; Choi, Yeong‐Hoon; Schmack, Bastian; Kallenbach, Klaus; Ruhparwar, Arjang; Eghbalzadeh, Kaveh; Dohmen, Pascal M.; Kretzler, Matthias; Wippermann, Jens; Wahlers, Thorsten; Popov, Aron‐Frederik; Simón, A.; Weymann, Alexander

doi:10.12659/msmbr.894840

Cited by 36 publications

(26 citation statements)

References 16 publications

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“…In a study in 13 patients with TAH, Ramirez et al found that bleeding complications occur generally between postoperative days 1 and 3 [12]. Patients with mechanical assist devices are prone to suffer from thrombotic events [13–16], device malfunctioning, wound infections, and bleeding complications.…”

Section: Discussionmentioning

confidence: 99%

Total Artificial Heart Implantation After Undifferentiated High-Grade Sarcoma Excision

Kremer¹,

Farag²,

Arif³

et al. 2016

Med Sci Monit Basic Res

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BackgroundTotal artificial heart (TAH) implantation in patients with aggressive tumor infiltration of the heart can be challenging.Case ReportWe report on a patient with a rare primary undifferentiated high-grade spindle cell sarcoma of the mitral valve and in the left atrium, first diagnosed in 2014. The referring center did a first resection in 2014. In the course of 17 months, computer tomography (CT) scan again showed massive invasion of the mitral valve and left atrium. Partial resection and mitral valve replacement was not an option. We did a subtotal heart excision with total artificial heart implantation. In this report we discuss complications, risk factors, and perioperative management of this patient.ConclusionsPatients with aggressive tumors of the heart can be considered for TAH implantation.

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Section: Discussionmentioning

confidence: 99%

Total Artificial Heart Implantation After Undifferentiated High-Grade Sarcoma Excision

Kremer¹,

Farag²,

Arif³

et al. 2016

Med Sci Monit Basic Res

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“…Other complications related to LVAD infections can include hemorrhagic stroke and mycotic aneurysm. Patients with heart failure are already at risk of thrombosis, and increased infectious complications and coagulopathy associated with LVADs increases the risk of device thrombosis and stroke (reviewed in [54]). Aggarwal et al [55] studied the relationship between bacteremia and stroke in LVAD patients in a retrospective chart review study.…”

Section: Cerebrovascular Microbleeds/stroke/mycotic Aneurysmmentioning

confidence: 99%

Left Ventricular Assist Device Infections

Skalweit¹

2018

Advanced Concepts in Endocarditis

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Left ventricular assist device (LVAD) infections are important causes of morbidity and mortality in patients who receive these mechanical circulatory supports as a bridge to transplantation (BTT) or as destination therapy (DT) (for individuals who are not candidates for cardiac transplant). Infections are more common among persons who received pulsatile flow LVADs as opposed to newer continuous flow (CF) devices. Other risk factors for infection include obesity, renal failure, depression and immunosuppression. An LVAD infection increases the risk of infections in persons who undergo cardiac transplantation. Infections include percutaneous site, driveline, pump pocket and pump/cannula infections; sepsis, bacteremia, mediastinitis and endocarditis. Diagnosis is achieved by monitoring LVAD flow parameters and observing typical clinical and laboratory manifestations of infection. Imaging such as PET-CT or SPECT-CT imaging can be helpful to establish a diagnosis of pump pocket infection. Echocardiography may aid in detecting native valve endocarditis and thrombus associated with the LVAD. The most common pathogens include Staphylococcus, Corynebacterium, Enterococcus, Pseudomonas and Candida spp. Treatment requires targeted antimicrobials plus surgical debridement of infected tissue and device components. In cases of pump/cannula/LVAD endocarditis, especially if fungal pathogens or Mycobacterium chimaera are involved, LVAD removal/reimplantation vs. transplant is necessary, combined with extended antimicrobial therapy.

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“…The modern treatment of heart failure is often associated with multiple surgical procedures and devices with potential complications (1,2). Due to the fact that HTX is gradually becoming a redo procedure, even more devices and strategies are being developed to facilitate faster organ offers (3,4).…”

Section: Palacos Bone Cement Is a Suitable Treatment For Sternal Recomentioning

confidence: 99%

Palacos Bone Cement Is a Suitable Treatment for Sternal Reconstruction in Patients After Total Artificial Heart Implantation Undergoing Heart Transplantation

et al. 2016

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Continuous-Flow Left Ventricular Assist Device Thrombosis: A Danger Foreseen is a Danger Avoided

Cited by 36 publications

References 16 publications

Total Artificial Heart Implantation After Undifferentiated High-Grade Sarcoma Excision

Total Artificial Heart Implantation After Undifferentiated High-Grade Sarcoma Excision

Left Ventricular Assist Device Infections

Palacos Bone Cement Is a Suitable Treatment for Sternal Reconstruction in Patients After Total Artificial Heart Implantation Undergoing Heart Transplantation

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