Total Artificial Heart Implantation After Undifferentiated High-Grade Sarcoma Excision

Kremer, Jamila; Farag, Mina; Arif, Rawa; Brcic, Andreas; Sabashnikov, Anton; Schmack, Bastian; Popov, Aron‐Frederik; Kretzler, Matthias; Dohmen, Pascal M.; Ruhparwar, Arjang; Weymann, Alexander

doi:10.12659/msmbr.901526

Cited by 8 publications

(4 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The role of chemotherapy or radiation therapy is controversial, and radical resection of the tumor seems to be the best treatment option [Xiao 2020]. Thus, alternative strategies, such as radical tumor resection along with the following techniques (heart transplant, total artificial heart, and auto-transplant), can be considered even though tumor recurrence cannot totally be avoided [Xiao 2020;Kremer 2016;Reardon 2006]. In the present case, the whole left atrium and some crucial adjacent tissue were infiltrated by the liposarcoma.…”

Section: Discussionmentioning

confidence: 79%

Subtotal Resection for the Symptom Relief of a Fatal and Aggressive Primary Cardiac Liposarcoma: A Case Report

Kong

Fan

2020

HSF

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 79%

Subtotal Resection for the Symptom Relief of a Fatal and Aggressive Primary Cardiac Liposarcoma: A Case Report

Kong

Fan

2020

HSF

View full text Add to dashboard Cite

show abstract

“…Heart transplantation may be an option for patients with sarcomas when there is no evidence of metastases; however, it has been associated with the recurrence of malignancy and new tumours stimulated by immunosuppression [ 11 ]. The guidelines regarding heart transplantation as candidacy for malignancies are unclear [ 12 , 13 ]. Total artificial heart implantation for spindle cell sarcoma was also reported to have poor outcomes due to the risk and complications [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Spindle cell sarcoma of the right atrium causing right atrial pseudoaneurysm: a case report and review of the literature

Wang

Dong

Wei-jun

et al. 2021

J Cardiothorac Surg

View full text Add to dashboard Cite

Background Spindle cell sarcomas of the right atrium are extremely rare primary cardiac tumours, with very few cases reported in the medical literature. Pseudoaneurysms caused by cardiac spindle cell sarcoma have never been reported worldwide. Case presentation A 32-year-old woman was referred to our hospital for recurrent pericardial haemorrhagic effusion and pleural effusion. Three-dimensional transthoracic echocardiogram, contrast chest CT, and contrast MRI revealed a pseudoaneurysm on the right side of the right atrium with a thrombus. There was a defect between the pseudoaneurysm and the right atrium. PET-CT suggested that FDG metabolism inhomogeneity increased in the mass in the right atrium. Exfoliative cytology detection of massive pericardial effusion and pleural effusion revealed no tumour cells. Spindle cell sarcoma of the right atrium was not confirmed until the patient underwent right thoracic exploration and biopsy. Before a confirmed diagnosis, symptomatic treatment, such as chest effusion and pericardium effusion drainage, and transfusion of red blood cells were mainly used to relieve the patient’s symptoms. Unfortunately, the patient was lost to optimal treatments and passed away 20 days after the pathological diagnosis was made. Conclusion The prognosis of spindle cell sarcomas remains poor due to delays in diagnosis, early metastasis and few available therapeutic options. Recurrent pericardial effusion and pleural effusion, especially in the nature of haemorrhagic effusion, and/or right atrial pseudoaneurysm shown on the transthoracic echocardiogram must be considered and highly suspected as malignancy by patients and physicians. If the diagnosis cannot be confirmed, histopathology should be performed as soon as possible to avoid losing the best treatment opportunity.

show abstract

“…They generally possess a poor prognosis with overall survival ranging from 6 to 12 months [20,21] Symptoms related to cardiac sarcomas are variable and may vary from specific cardiac symptoms (pericardial effusions with tamponade, arrhythmias, valvular dysfunction, intracardiac blood flow abnormalities, congestive heart failure, peripheral embolization with systemic deficits, dyspnea, chest pain, syncope, hemoptysis, sudden cardiac death) to general symptoms of neoplastic diseases like fever, malaise and weight loss in general is very dificult to exicesed entire and sometimes require to replace the heart [22][23][24] A review of the published papers appears to indicate that there are two distinct types. The one type is cystic and is discovered incidentally as a superficially situated lesion lined by ciliated epithelium.…”

Section: Discussionmentioning

confidence: 99%

56 Years of Experience of Primary Tumors of The Heart

Benetti¹

2019

SCSOAJ

View full text Add to dashboard Cite

22 large autopsy series reported by Mc Allister et al [1]. showed the frequency of primary cardiac tumors is ∼0.02%, corresponding to 200 tumors in 1 million autopsies. Around 75% are benign; nearly half are myxomas; and a majority of the rest are lipomas, papillary fibroelastomas, and rhabdomyomas [1]. Sixty years ago in 1954, Crafoord [2] was the first to excise an atrial myxoma on cardiopulmonary bypass [2]. Today, cardiac tumors represent around 0.3% of all open-heart surgeries [3]. From 1963 to 2019 7,600 open Heart operations were done in ouers diferents centers in Argentina. 23 Patients (0.3%) were operated on of primary Tumor of the heart. In this report, we review the surgical experience and results of cardiac tumors during this 56 years. Material and Methods 15 patients were female (65%) The average age was 52 years (1967) The clinical presentation was Dyspnea 8 (34,8%) Arrtymia 6 (26,08%) ChestPain 3 (13%), Emboli 2 (8,7%), Syncope 2 (8,7%), Accidentaly 2(8,7%). 17 were Myxomas 17 cases (74%) 15 (88%) left and 2 (12%) rigth. Papillary Fibroelastoma 4 (17,4%) sarcoma 1 (4,4%) Cyst 1(4,4%) Surgical Thecnique: all of the patients in this serie were operated on with Cardiopulmonary Byapass 21 througth Sternotomy and 2 Minimally invasive Rigth Thoracotomy. In 20 patients the tumor was excised under direct visión with and without magnification. In 3 patients Video 3 D was used to improved the visualization during the operation. ResultsThe operative mortality was 1 case (4,3%). The patient with a Sarcoma died inmediatly after the operation; the entire Rigth Ventricle was invaded by the Tumor the exsicion was very dificult.The rest of the patients survived the operation At the average of 29,8 years of follow up of the 17 patients with Myxmomas 6 (35%) died ,no recurrence of the Tumor were found in this patients. In the patients with Papillary Fibroelastoma 2 patients were lost of follow up one died at 12 years after de operation and the other is alive The patient withCyst died at 8 years after the operation.

show abstract

Total Artificial Heart Implantation After Undifferentiated High-Grade Sarcoma Excision

Cited by 8 publications

References 16 publications

Subtotal Resection for the Symptom Relief of a Fatal and Aggressive Primary Cardiac Liposarcoma: A Case Report

Subtotal Resection for the Symptom Relief of a Fatal and Aggressive Primary Cardiac Liposarcoma: A Case Report

Spindle cell sarcoma of the right atrium causing right atrial pseudoaneurysm: a case report and review of the literature

56 Years of Experience of Primary Tumors of The Heart

Contact Info

Product

Resources

About