Continuous glucose monitoring: A review of biochemical perspectives and clinical use in type 1 diabetes

Girardin, Celine; Huot, Céline; Gonthier, Monique; Delvin, Edgard

doi:10.1016/j.clinbiochem.2008.09.112

Cited by 91 publications

(58 citation statements)

References 52 publications

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“…Moreover the results presented in this article represent a novelty since amperometric biosensors for continuous monitoring have already been developed for glucose (Girardin et al, 2009), and other endogenous compounds (Frost and Meyerhoff, 2002), but no enzymatic amperometric biosensors have been reported so far for real-time monitoring of drugs.…”

Section: Discussionmentioning

confidence: 99%

Continuous monitoring of Naproxen by a cytochrome P450-based electrochemical sensor

Baj-Rossi

Jost²,

Cavallini

et al. 2014

Biosensors and Bioelectronics

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a b s t r a c tThis paper reports the characterization of an electrochemical biosensor for the continuous monitoring of Naproxen based on cytochrome P450. The electrochemical biosensor is based on the drop-casting of multi-walled carbon-nanotubes (MWCNTs) and microsomal cytochrome P4501A2 (msCYP1A2) on a graphite screen-printed electrode (SPE).The proposed biosensor was employed to monitor Naproxen (NAP), a well-known anti-inflammatory compound, through cyclic voltammetry. The dynamic linear range for the amperometric detection of NAP had an upper limit of 300 mM with a corresponding limit of detection (LOD) of 16 7 1 mM (S/N¼3), which is included in NAP physiological range (9-300 mM). The MWCNT/msCYP1A2-SPE sensor was also calibrated for NAP detection in mouse serum that was previously extracted from mice, showing a slightly higher LOD (33718 mM).The stability of the msCYP1A2-based biosensor was assessed by longtime continuous cyclic voltammetric measurements. The ability of the sensor to monitor drug delivery was investigated by using a commercial micro-osmotic pump. Results show that the MWCNT/msCYP1A2-SPE sensor is capable of precisely monitoring the real-time delivery of NAP for 16 h. This work proves that the proposed electrochemical sensor might represent an innovative point-of-care solution for the personalization of drug therapies, as well as for pharmacokinetic studies in both animals and humans.

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Section: Discussionmentioning

confidence: 99%

Continuous monitoring of Naproxen by a cytochrome P450-based electrochemical sensor

Baj-Rossi

Jost²,

Cavallini

et al. 2014

Biosensors and Bioelectronics

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“…Hence, the ability of simultaneous measurements of 2a and 0 2s becomes critical to reach high sensitivity glucose concentration. 7,19 As a result, this proposed method based on DPPDW can measure the reduced scattering coe±cient and absorption coe±cient simultaneously at higher sensitivity using a moderate beat frequency of heterodyne signal. This becomes one of the advantages of this setup vs conventional methods of glucose monitoring noninvasively for diabetes.…”

Section: Discussionmentioning

confidence: 99%

Glucose detection in a highly scattering medium with diffuse photon-pair density wave

Chang

et al. 2017

J. Innov. Opt. Health Sci.

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We propose a novel optical method for glucose measurement based on di®use photon-pair density wave (DPPDW) in a multiple scattering medium (MSM) where the light scattering of photonpair is induced by refractive index mismatch between scatters and phantom solution. Experimentally, the DPPDW propagates in MSM via a two-frequency laser (TFL) beam wherein highly correlated pairs of linear polarized photons are generated. The reduced scattering coe±cient 0 2s and absorption coe±cient 2a of DPPDW are measured simultaneously in terms of the amplitude and phase measurements of the detected heterodyne signal under arrangement at di®erent distances between the source and detection¯bers in MSM. The results show that the sensitivity of glucose detection via glucose-induced change of reduced scattering coe±cient ( 0 2s ) is 0.049% mM À1 in a 1% intralipid solution. In addition, the linear range of 0 2s vs glucose concentration implies that this DPPDW method can be used to monitor glucose concentration continuously and noninvasively subcutaneously.

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“…• Screening and Diagnostics: Biochemical and optical sensors are used for point-of-care monitoring and diagnostics applications, including blood and tissue analysis , Girardin, et al, 2009. Biosensors can be used to identify bacterial infection, drugs, hormones, and proteins levels in biological samples (Swensen, et al, 2009)(McLachlan, et al, 2011.…”

Section: Healthcarementioning

confidence: 99%

Sensing and Sensor Fundamentals

McGrath¹,

Scanaill²

2013

Sensor Technologies

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Sensors utilize a wide spectrum of transducer and signal transformation approaches with corresponding variations in technical complexity. These range from relatively simple temperature measurement based on a bimetallic thermocouple, to the detection of specific bacteria species using sophisticated optical systems. Within the healthcare, wellness, and environmental domains, there are a variety of sensing approaches, including microelectromechanical systems (MEMS), optical, mechanical, electrochemical, semiconductor, and biosensing. As outlined in Chapter 1, the proliferation of sensor-based applications is growing across a range of sensing targets such as air, water, bacteria, movement, and physiology. As with any form of technology, sensors have both strengths and weaknesses. Operational performance may be a function of the transduction method, the deployment environment, or the system components. In this chapter, we review the common sensing mechanisms that are used in the application domains of interest within the scope of this book, along with their respective strengths and weaknesses. Finally, we describe the process of selecting and specifying sensors for an application.

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Continuous glucose monitoring: A review of biochemical perspectives and clinical use in type 1 diabetes

Cited by 91 publications

References 52 publications

Continuous monitoring of Naproxen by a cytochrome P450-based electrochemical sensor

Continuous monitoring of Naproxen by a cytochrome P450-based electrochemical sensor

Glucose detection in a highly scattering medium with diffuse photon-pair density wave

Sensing and Sensor Fundamentals

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