Continuous glucose monitoring systems in the service of artificial pancreas

Eigner, György; Sas, Péter István; Kovács, Levente

doi:10.1109/saci.2014.6840047

Cited by 7 publications

(5 citation statements)

References 47 publications

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“…With increasing glucose concentration the amplitude of S 21 increases. This coherence is described by (1) and (2). The phase of S 21 is shown in Fig.…”

Section: Resultsmentioning

confidence: 96%

“…Normal fasting blood glucose (BG) levels are in the range of 70-110 mg/dl. A slight deviation from the normal BG level can lead to a dysfunction of the energy-balance and the carbohydrate toleration [2]. Therefore, for the diagnosis and treatment of diabetes, it is imperative to measure and control the BG level accurately and frequently.…”

Section: Introductionmentioning

confidence: 99%

“…To overcome these problems, non-invasive continuousglucose-monitoring (CGM) is a promising alternative [2].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Towards Realisation of a Non-Invasive Blood Glucose Sensor Using Microstripline

Zeising¹,

Kirchner²,

Khalili³

et al. 2021

Preprint

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In this paper, the design of a microwave based noninvasive glucose sensor at the operating frequency of 19 GHz is presented. Worldwide, about 451 million adults suffer from diabetes. For optimal therapy, people with diabetes should monitor their blood glucose level continuously over the day. For that purpose non-invasive microwave based glucose sensors are under research. Non-invasive microwave based glucose sensors must automatically perform continuous measurements with a high and stable accuracy. However, there exists no reliable noninvasive microwave based glucose sensor up to now. The proposed sensor is designed based on a two-port microstripline (MSL) network. Water with various glucose concentration from 0 to 500 mg/dl is placed in a slot between the two ports. The simulation results show that the phase change in the reflection coefficient for the various glucose concentration depends on the matching. The measurement of the glucose concentration 10 mg/dl can be realized by applying a taper ground plane as a matching technique decreasing reflections at the interface between the microstripline substrate and the water. The proposed sensor achieves a sensitivity of 2 ° phase change per 10 mg/dl glucose concentration variation. In the future, the simulation results should be validated in an experimental setup. <br>

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“…With increasing glucose concentration the amplitude of S 21 increases. This coherence is described by (1) and (2). The phase of S 21 is shown in Fig.…”

Section: Resultsmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Towards Realisation of a Non-Invasive Blood Glucose Sensor Using Microstripline

Zeising¹,

Kirchner²,

Khalili³

et al. 2021

Preprint

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show abstract

“…Due to technological limitations, the data of sensor measurements are available every five minutes on average, i.e. a sampling time of five minutes can be expected in the case of automated algorithms, which greatly complicates the design of a continuous regulator [9,10].…”

Section: Sensormentioning

confidence: 99%

Fully automated insulin delivery: artificial pancreas

Barkai

2023

Egészségtudományi Közlemények

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Despite the increasing use of new treatment options, the glycaemic control of most diabetes patients is not satisfactory. However, a clear advantage is documented in the subpopulation of patients applying advanced technologies. Nevertheless, there is a need to improve the replacement of islet function and to check the achievement of treatment goals in individuals with diabetes. Aiming to fulfil these requirements, new technologies need to attain. Parallel development of insulin pumps and continuous glucose monitoring devices lead to automated insulin delivery systems. The future development goal is to achieve systems not dependent on user inputs, e.g. the fully closed loop system (artificial pancreas). The biggest barriers are the non-physiological insulin delivery and glucose monitoring subcutaneous/interstitial) of the systems used currently, therefore further research will establish the long-term benefits of emerging technologies in the care of diabetes individuals.

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“…Beside its several benefits CGMS has also some disadvantages mostly from control engineering point of view: sensors measurements are done only every 5 minutes. Implantable CMGS have been also appeared, but these are not available on the market, yet [28].…”

Section: Introductionmentioning

confidence: 99%

System Engineering Approach of Diabetes Treatment

́acs¹,

Eigner²

2016

Int J Diabetes Clin Diagn

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The paper gives a short system engineering review on the treatment of diabetes covering control engineering and mathematical modeling issues. The Artificial Pancreas (AP) concept is discussed together with the Intensive Care (ICU) idea for automatic treatment of diabetic patients. This highly interdisciplinary concept involves beyond medical sciences, control engineering and biomedical engineering knowledge. Having already developed continuous glucose sensor devices and highly performant insulin pumps, the automatic control concept could be an efficient solution for millions of people living with diabetes for accurate metabolic conditions management.

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Continuous glucose monitoring systems in the service of artificial pancreas

Cited by 7 publications

References 47 publications

Towards Realisation of a Non-Invasive Blood Glucose Sensor Using Microstripline

Towards Realisation of a Non-Invasive Blood Glucose Sensor Using Microstripline

Fully automated insulin delivery: artificial pancreas

System Engineering Approach of Diabetes Treatment

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