Contrast-enhanced ultrasound (CEUS) and perfusion imaging using VueBox®

Wiesinger, Isabel; Jung, F.; Jung, Ernst Michael

doi:10.3233/ch-201040

Cited by 38 publications

(24 citation statements)

References 39 publications

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“…However, since no Doppler spectral analysis, no elastography and no contrast enhanced ultrasound technology is integrated in the present mobile ultrasound devices, high-end ultrasound remains the imaging technique that allows an even more detailed analysis of abdominal and pulmonary pathologies including the evaluation of microcirculation, as current studies show [12][13][14][15][16]. Nevertheless, under the premise of proper training, POCUS shows advantages in fast and critical situations or in intensive care units.…”

Section: Discussionmentioning

confidence: 99%

Wireless point-of-care ultrasound: First experiences with a new generation handheld device

Jung

Dinkel

Verloh

et al. 2021

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AIM: To evaluate the diagnostic reliability of a new generation wireless point-of care ultrasound device for abdominal and thoracic findings. MATERIAL AND METHODS: 40 patients (16 females, 24 males 19 –80 years, on average 56.1 years) were scanned by an experienced examiner using the new wireless Vscan Air device for abdominal and thoracic findings. The probe frequencies were 2–5 MHz (convex probe) and 3–12 MHz for the linear probe. As a reference standard, all patients were also examined using high-end ultrasound (LOGIQ E9/10). Results were interpreted independently by two examiners in consensus, also with regard to the image quality (0–4, from not assessable = 0, to excellent 4). RESULTS: In all 40 patients (100%) examination with conventional high-end ultrasound and the Vscan Air ultrasound device was feasible. Sensitivity, specificity, positive and negative predictive value for the diagnosis of abdominal and thoracic findings were 63.3%, 100%, 100%, and 40%, respectively. Most main diagnostic findings were detected using the mobile device compared to the high-end ultrasound. Limitations were found regarding characterization and classification of hepatic and renal tumorous lesions. Image quality revealed mostly minor diagnostic limitations for the mobile device, mean 2.9 (SD –0.300) and was excellent or with only minor diagnostic limitations for conventional high-end ultrasound, mean 3.25 (SD –0.438). CONCLUSION: Due to its easy application and its high diagnostic reliability, point-of-care ultrasound systems of the latest generation represent a valuable imaging method for the primary assessment of abdominal and thoracic findings, especially in patients on intensive care units or in emergency situations.

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Section: Discussionmentioning

confidence: 99%

Wireless point-of-care ultrasound: First experiences with a new generation handheld device

Jung

Dinkel

Verloh

et al. 2021

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“…Using false colors, red for instance, shows fast and high contrast media enhancement, decreasing from yellow to orange down to green, blue and purple shades, which show lower perfusion, according to European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) guidelines [ 1 ]. By using additional parameters, such as wash-in rate, rise time (RT), and wash-out rate, local perfusion changes of solid lesions can be detected [ 3 , 6 ].…”

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confidence: 99%

“…For these non-hepatic indications, CEUS perfusion is applied. Regarding the evaluation of early therapy success in gastrointestinal tumors, CEUS perfusion has been successfully evaluated [ 4 , 6 , 9 ].…”

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confidence: 99%

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Contrast-enhanced ultrasound perfusion imaging of organs

2021

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In multimodal radiologic imaging, contrast-enhanced ultrasound (CEUS) is increasingly used. One of the advantages of CEUS is the possibility of repeated application of contrast media without decreasing renal function or affecting the thyroid gland. Small solid liver lesions can be diagnosed and detected with high accuracy. Moreover, solid lesions in other abdominal organs can also be characterized. Frequent applications for solid lesions in the near field concern thyroid tumors and lymph nodes. For prostate diagnostics, CEUS can be used with an endorectal probe and perfusion imaging. This review explains how the additional (semi-)quantitative perfusion analysis, especially time–intensity curve (TIC) analyses, and wash-in/wash-out kinetics of integrated or external perfusion software programs facilitate new options in dynamic assessment of microvascularization during tumor follow-up care and even minimally invasive tumor therapy.

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“…Contrast-enhanced ultrasonography (CEUS) is an ultrasound diagnostic technique using intravenous injection of microbubble contrast agents and real-time harmonic gray-scale sonography [13][14][15][16], which can effectively evaluate blood perfusion in tissue and partial microcirculation for solid organs [17][18][19].…”

Section: Introductionmentioning

confidence: 99%

The diagnostic value of contrast-enhanced ultrasound for cervical tuberculous lymphadenitis

Zhao

Shao

et al. 2022

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OBJECTIVE: To investigate the value of contrast-enhanced ultrasound (CEUS) for the diagnosis of cervical tuberculous lymphadenitis (CTL). METHODS: The cohort study included 203 consecutive patients diagnosed with cervical lymph node. Before pathological or laboratory confirmation, all patients underwent CEUS examination, and the imaging findings were analyzed afterward. The diagnostic efficiency of the CEUS imaging findings of CTL was evaluated. RESULTS: Nighty-seven patients of the 203 (47.8%) were pathologically or laboratory confirmed with a CTL diagnosis while the remainder (52.2%) were diagnosed with non-tuberculous lymphadenitis. Regarding the imaging findings of CEUS, it was more common in CTL patients to find a pattern of heterogeneous enhancement inside the lymph nodes relative to non-tuberculous patients [81.44% (79/97) vs 15.09% (16/106), P < 0.01]. The sensitivity of the feature in diagnosis for CTL was 81.44% and the specificity was 84.91%, resepectively. Furthermore, a pattern of peripheral rim-like enhancement had been notable in CTL patients compared with non-tuberculous patients [86.60% (84/97) vs 12.26% (13/106), P < 0.01], associating with a diagnostic sensitivity of 86.60% and a specificity of 87.74% . When it came to the combination of both imaging findings mentioned above, the features were more prominent in CTL patients than compared with non-tuberculous patients [74.23% (72/97) vs 5.66% (6/106), P < 0.01], with a diagnostic sensitivity of 74.23% and a high specificity of 94.34% . Regarding area under curve (AUC) for the ROC analysis, the feature of internal heterogeneous enhancement, peripheral rim-like enhancement, and both features were 0.832, 0.872, and 0.843. CONCLUSIONS: CEUS patterns of heterogeneous enhancement and peripheral rim-like enhancement of lymph nodes are helpful characteristics for the diagnosis of CTL.

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Contrast-enhanced ultrasound (CEUS) and perfusion imaging using VueBox®

Cited by 38 publications

References 39 publications

Wireless point-of-care ultrasound: First experiences with a new generation handheld device

Wireless point-of-care ultrasound: First experiences with a new generation handheld device

Contrast-enhanced ultrasound perfusion imaging of organs

The diagnostic value of contrast-enhanced ultrasound for cervical tuberculous lymphadenitis

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