Contrast-enhanced ultrasound of breast tumors: an initial experience

Kristiansen, Merete U; Martiniussen, Marit A; Larsen, Anne Sofie Frøyshov

doi:10.1177/20584601221097458

Cited by 3 publications

(2 citation statements)

References 10 publications

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“…In the evaluation, quantitative criteria drawn from the examination may be taken into account. 25 One of the advantages of ultrasound is in detecting cystic masses. Similar to mammography, the American College of Radiology has also developed a standardized language for ultrasound reading and reporting according to BIRADS.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy of Contrast-Enhanced Ultrasound to Differentiate Benign and Malignant Breast Lesions

Pambudi

2023

JARMHS

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Cancer of the breast is caused by a cluster of abnormal breast cells that continue to divide and spread throughout the breast. These cells eventually aggregate as a lump in the affected breast. If the cancerous tumor is not treated, the cancer cells may spread to other areas of the body through a process known as metastasis. A metastasis may develop in the lymph nodes located in the axilla or those located above the scapula. In addition, cancer cells have the ability to colonize the bones, lungs, liver, skin, and even the space directly under the skin. Cancer of the breast tissue is a malignancy that can start from either the ductal or lobule epithelium of the breast. Breast cancer is the most common kind of cancer in women. The ability of ultrasonography to identify cystic masses is one of the technology's many strengths. According to BIRADS, the American College of Radiology has also developed a standardized language for the reading and reporting of ultrasounds, which is quite similar to the language used for mammography. Shape of the mass, borders, orientation, kind of posterior acoustic, lesion boundaries, and echo pattern were the characteristics that were described. CEUS is an imaging technology that evaluates breast lesions by analyzing their qualitative qualities as well as their quantitative aspects. The detection of lymphatic channels and sentinel lymph nodes can be done using this method, and it is practical and effective.

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Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy of Contrast-Enhanced Ultrasound to Differentiate Benign and Malignant Breast Lesions

Pambudi

2023

JARMHS

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“…We propose CEUS as the first imaging modality for CT-detected lesions of unknown dignity [9]. CEUS is a feasible method of examining blood flow in malignant breast tumors [10].…”

Section: Intradermal and Subcutaneous Injections Of Ultrasoundmentioning

confidence: 99%

Contrast Enhance Ultrasonography for Oncology

D¹,

Kumar²,

Suman³

et al. 2023

Act Scie Canbio

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Background: Ultrasonography is a diagnostic method for determining the diagnosis of various diseases. It is non-invasive, nonionizing and very cost effective diagnostic in compare to Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) scan.Similarly contrast enhanced Ultrasonography (CEUSG) uses contrast agents used intravenously and sometimes intravesically in some cases which improve the diagnostic sensitivity, specificity and accuracy. Conclusion:Contrast-enhanced Ultrasonography (CEUSG) has a prominent role in lesion characterization with a diagnostic accuracy comparable with CT and MRI scan. CEUSG is a fast, cheap and widely used technique in most of the oncological diseases with additional benefit of lack of nephrotoxicity and radiation.

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Radiogenomic analysis of the correlation between clinical, ultrasound characteristics and immune-related genes in breast cancer

Dou,

Chen,

Liu

et al. 2024

Preprint

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Background: Breast cancer is the most commonly diagnosed cancer worldwide. Breast cancer screening, early diagnosis, and standardized treatment can effectively reduce the mortality of patients. Breast color Doppler ultrasound plays a significant role in the non-invasive screening and diagnosis of breast cancer. The application of immunotherapy for breast cancer can significantly prolong the overall survival rates of patients with advanced breast cancer, which is an important research area of breast cancer treatment. This study analyzed the correlation between the clinical and ultrasound characteristics of breast cancer and immune-related genes. Methods: First, differential expression of immune-related genes were obtained using the GEO and IMMPORT database. Then, differentially expressed immune-related genes related to the overall survival of breast cancer were obtained using the GEPIA and Kaplan-Meier plotter platforms. Additionally, clinical, ultrasound characteristics and pathological specimens of breast cancer patients’ tumors were collected. Transcriptome sequencing and immunohistochemical staining were performed on the tumor specimens to obtain gene expression. Results: CXCL2, MIA, NR3C2, PTX3, S100B, SAA1, SAA1, and CXCL9 genes were correlated with each other and with clinical and ultrasonic characteristics. The high expression of MIA was related to the positive expression of PR in breast cancer. The low expression of NR3C2 was correlated with the clinical characteristics of tumor size≥20mm, later stage, Her-2 positive, Ki-67≥20%. NR3C2 was negatively correlated with the value of PKI and AUC in contrast-enhanced ultrasound parameters, and positively correlated with the value of AT and TTP. The expression of the PTX3 gene was also negatively correlated with the value of PKI and Emax of shear wave elastography. SAA2 was related to the presence or absence of burrs on the edge of the tumor characterized by ultrasound. The expression of the CXCL9 gene was associated with the age of onset and tumor stage. Conclusions: In this study, 8 differentially expressed immune-related genes related to the overall survival rate of breast cancer were screened, which can be further studied in the subsequent immunotherapy of breast cancer. Some clinical and ultrasonic characteristics of breast cancer were significantly correlated with immune-related genes, such as NR3C2, SAA2, and CXCL9. Further analysis of these genes provides new ideas for the diagnosis and treatment of breast cancer.

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Contrast-enhanced ultrasound of breast tumors: an initial experience

Cited by 3 publications

References 10 publications

Diagnostic Accuracy of Contrast-Enhanced Ultrasound to Differentiate Benign and Malignant Breast Lesions

Diagnostic Accuracy of Contrast-Enhanced Ultrasound to Differentiate Benign and Malignant Breast Lesions

Contrast Enhance Ultrasonography for Oncology

Radiogenomic analysis of the correlation between clinical, ultrasound characteristics and immune-related genes in breast cancer

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