Contribution to linearly programmed temperature gas chromatography

Santiuste, J. M.; Tarján, G.; Ullrich, Ede; Takács, J.

doi:10.1016/j.chroma.2007.12.025

Cited by 12 publications

(3 citation statements)

References 101 publications

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“…This apparatus was controlled by a computer system type "HP ChemStation", which allowed us to monitor MS and total ions gas chromatography (GC-TIC) analysis. CAEO compounds were identified by establishing their retention index (RI) following the Van Den Dool method [66] (Determined using n-alkanes (C9-C31) series), and also by computer matching of their MS identities with the recorded data library (Wiley 09, Nist 2002). Finally, the chemical characterization was completed by matching the fragmentation patterns of MS with those published in the literature.…”

Section: Gas Chromatography-mass Spectrometry (Gc-ms) Analysismentioning

confidence: 99%

Antioxidant, Volatile Compounds; Antimicrobial, Anti-Inflammatory, and Dermatoprotective Properties of Cedrus atlantica (Endl.) Manetti Ex Carriere Essential Oil: In Vitro and In Silico Investigations

et al. 2023

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Cedrus atlantica (Endl.) Manetti ex Carriere is an endemic tree possessing valuable health benefits which has been widely used since time immemorial in international traditional pharmacopoeia. The aim of this exploratory investigation is to determine the volatile compounds of C. atlantica essential oils (CAEOs) and to examine their in vitro antimicrobial, antioxidant, anti-inflammatory, and dermatoprotective properties. In silico simulations, including molecular docking and pharmacokinetics absorption, distribution, metabolism, excretion, and toxicity (ADMET), and drug-likeness prediction were used to reveal the processes underlying in vitro biological properties. Gas chromatography–mass spectrophotometry (GC-MS) was used for the chemical screening of CAEO. The antioxidant activity of CAEO was investigated using four in vitro complementary techniques, including ABTS and DPPH radicals scavenging activity, ferric reductive power, and inhibition of lipid peroxidation (β-carotene test). Lipoxygenase (5-LOX) inhibition and tyrosinase inhibitory assays were used for testing the anti-inflammatory and dermatoprotective properties. GC-MS analysis indicated that the main components of CAEO are β-himachalene (28.99%), α-himachalene (14.43%), and longifolene (12.2%). An in vitro antimicrobial activity of CAEO was examined against eleven strains of Gram-positive bacteria (three strains), Gram-negative bacteria (four strains), and fungi (four strains). The results demonstrated high antibacterial and antifungal activity against ten of them (>15 mm zone of inhibition) using the disc-diffusion assay. The microdilution test showed that the lowest values of MIC and MBC were recorded with the Gram-positive bacteria in particular, which ranged from 0.0625 to 0.25 % v/v for MIC and from 0.5 to 0.125 % v/v for MBC. The MIC and MFC of the fungal strains ranged from 0.5 to 4.0% (MIC) and 0.5 to 8.0% v/v (MFC). According to the MBC/MIC and MFC/MIC ratios, CAEO has bactericidal and fungicidal activity. The results of the in vitro antioxidant assays revealed that CAEO possesses remarkable antioxidant activity. The inhibitory effects on 5-LOX and tyrosinase enzymes was also significant (p < 0.05). ADMET investigation suggests that the main compounds of CAEO possess favorable pharmacokinetic properties. These findings provide scientific validation of the traditional uses of this plant and suggest its potential application as natural drugs.

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Section: Gas Chromatography-mass Spectrometry (Gc-ms) Analysismentioning

confidence: 99%

Antioxidant, Volatile Compounds; Antimicrobial, Anti-Inflammatory, and Dermatoprotective Properties of Cedrus atlantica (Endl.) Manetti Ex Carriere Essential Oil: In Vitro and In Silico Investigations

et al. 2023

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“…t Rp is the programmed temperature retention time (min), r is the heating rate (K/min or °C/min), z and z + 1 are the carbon (atom) numbers of the n ‐alkanes eluted pre and post solute, and T 0 is the initial temperature (K or °C). The heating rate, r , is constant in the course of experiment, and it initials at the same time with the onset of the sample investigation 31,32

I_{DK} = 100 ([], \frac{t_{Rp} ((), x) - t_{Rp} ((), z)}{{tT}_{Rp} ((), z + 1) - t_{Rp} ((), z)} + z) .

…”

Section: Finite Sums Associated With Van Den Dool and Kratz Equation ...mentioning

confidence: 99%

“…The heating rate, r, is constant in the course of experiment, and it initials at the same time with the onset of the sample investigation. 31,32 I DK ¼ 100…”

Section: Identification Of Componentsmentioning

confidence: 99%

Calculation of retention indices of essential oils with the aid of the Van den Dool and Kratz equation and Bézier curves

Battaloğlu

2021

Math Methods in App Sciences

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The aim of this article is to study the relationships and models among the Van den Dool and Kratz equation, the gas chromatography (GC), and the Bézier curves constructed by aid of the Bernstein polynomials. Another aim of this article is to introduce open problems that contribute to real‐world problems involving mathematics, chemistry, and plant biology, including the Van den Dool and Kratz equation, the GC, and Bézier curves. Searching for the solutions of these problems may have qualities that will create the potential that can enter the field of study of many researchers. As a result of these goals, the usability of Bézier curves was investigated while determining the chemical composition of essential oil obtained from Potentilla aladaghensis Leblebici, by applying the retention index from the Van den Dool and Kratz equation and evaluating chemical compositions of the essential oil are characterized by GC–mass spectrometry (GC–MS). The Van den Dool and Kratz equation results have the potential to be used not only in the chemical compositions of the oils but also in applied mathematics and other fields. Moreover, we construct a new special finite sum. A lower bound and inequality are also given for the finite special sum involving the dead time associated with the isocratic step. Some applications and criticisms are given that include this lower bound and inequality for these sums and its effects on the chemical compositions of essential oil and the Van den Dool and Kratz equation.

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Liquid Phases for Gas ChromatographyUpdate based on the original article by Nicholas H. Snow,Encyclopedia of Analytical Chemistry, © 2000, John Wiley & Sons, Ltd.

Snow

2012

Encyclopedia of Analytical Chemistry

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In gas chromatography (GC), the liquid phase, also called the stationary phase, provides the medium in which the separation occurs. The magnitude of separation is given by the relative strengths of intermolecular interactions between analyte and stationary phase molecules, thus numerous liquids have been used over the years. The stationary phase can be coated onto a solid support and packed into a tube (packed column GC), or coated onto the wall of a capillary (capillary GC). Today, most GC analyses are performed using capillary columns.

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Contribution to linearly programmed temperature gas chromatography

Cited by 12 publications

References 101 publications

Antioxidant, Volatile Compounds; Antimicrobial, Anti-Inflammatory, and Dermatoprotective Properties of Cedrus atlantica (Endl.) Manetti Ex Carriere Essential Oil: In Vitro and In Silico Investigations

Antioxidant, Volatile Compounds; Antimicrobial, Anti-Inflammatory, and Dermatoprotective Properties of Cedrus atlantica (Endl.) Manetti Ex Carriere Essential Oil: In Vitro and In Silico Investigations

Calculation of retention indices of essential oils with the aid of the Van den Dool and Kratz equation and Bézier curves

Liquid Phases for Gas ChromatographyUpdate based on the original article by Nicholas H. Snow,Encyclopedia of Analytical Chemistry, © 2000, John Wiley & Sons, Ltd.

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