Control of peroxidizable compounds

Abstract

Provides information of the structure, examples, and safety considerations for compounds that can produce explosive peroxides.

Safe and Fast Flow Synthesis of Functionalized Oxazoles with Molecular Oxygen in a Microstructured Reactor

“…Nevertheless, molecular oxygen as an oxidizing agent is often neglected because of its propensity to form explosive mixtures or peroxides with many common solvents 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 5 and reagents, e.g., by autoxidation processes especially under harsh conditions. 18 This can be prevented by executing the reaction in microstructured reactors, where high temperatures and pressures can be applied in a safe and simple fashion. 19 The main advantage of microreactor technology is transport intensification due to microfluidic phenomena for mixing, heat transfer and high temperature leading to short residence times, faster mixing of miscible phases, improved heat transport and improved safety.…”

Cellulose‐Derived Functional Polyacetal by Cationic Ring‐Opening Polymerization of Levoglucosenyl Methyl Ether

“…However, we noticed that polymer 4 underwent crosslinking, even when stored at −20 °C, which could be avoided by the exclusion of oxygen or the addition of traces of a radical inhibitor, for example, butylated hydroxytoluene (BHT). It is thought that the allylic ether units in the polymer can form peroxide with atmospheric oxygen, and this peroxide can potentially act as radical initiator for the olefin crosslinking. Furthermore, the double bonds in 4 are amenable to modification through thiol–ene reactions and hydrogenation, for example (Scheme ) .…”

“…As mentioned above,the polymerization did not affect the olefin functionality of the carbohydrate rings.H owever,w e noticed that polymer 4 underwent crosslinking,e ven when stored at À20 8 8C, which could be avoided by the exclusion of oxygen or the addition of traces of ar adical inhibitor,f or example,butylated hydroxytoluene (BHT). It is thought that the allylic ether units in the polymer can form peroxide with atmospheric oxygen, [17] and this peroxide can potentially act as radical initiator for the olefin crosslinking.F urthermore, the double bonds in 4 are amenable to modification through thiol-ene reactions and hydrogenation, for example (Scheme 3). [18] Ther adical additions of methyl 3-mercaptopropionate using either azobisisobutyronitrile( AIBN) as ar adical source at 80 8 8Co rb enzophenone/UV light at room temperature were quantitative (polymer 5), as indicated by the complete disappearance of olefin protons in 1 HNMR spectra (see the Supporting Information).…”

Cellulose‐Derived Functional Polyacetal by Cationic Ring‐Opening Polymerization of Levoglucosenyl Methyl Ether

“…It is thought that the allylic ether units in the polymer can form peroxide with atmospheric oxygen, [17] and this peroxide can potentially act as radical initiator for the olefin crosslinking.F urthermore, the double bonds in 4 are amenable to modification through thiol-ene reactions and hydrogenation, for example (Scheme 3). It is thought that the allylic ether units in the polymer can form peroxide with atmospheric oxygen, [17] and this peroxide can potentially act as radical initiator for the olefin crosslinking.F urthermore, the double bonds in 4 are amenable to modification through thiol-ene reactions and hydrogenation, for example (Scheme 3).…”