The increase in the trains weight and their operation speeds leads to considerable growth of abrupt-variable, non-linear and one-phase traction loads. This, in its own turn, leads to significant deviations, unsymmetry and voltage harmonic distortions in 110-220 kV mains adjacent to traction substations of AC railroads. Significant deterioration in power quality factors is observed in Siberian and Far East regions where 110-220 kV main power transmission lines are immediately adjacent to Transsib traction substations; in this case, in points with lower levels of short circuit power, power quality factors exceed by far the permissible levels. The articles provides the results of studies aimed at solution of power quality enhancement is-sues for mains adjacent to traction substations of Trans-Siberian Railway. To enhance power quality in mains supplying traction substations, smart grid technologies can be used together with multiagent control systems. Technical solutions, based on the results obtained, are proposed that allow to bring the power quality factors to the regulatory values. Due to a big investments amount, an implementation of tar-get program is needed to resolve the large-scale issue of enhancing power quality in mains adjacent to traction substations of AC railroads.