Controlled ventilation using isoflurane with an in‐circle vaporiser

Wright, David; Brosnan, S.; Royston, B.; White, David C.

doi:10.1046/j.1365-2044.1998.365-az0510.x

Cited by 12 publications

(5 citation statements)

References 7 publications

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“…The proportion of expired gas that is re‐breathed is determined by the FGFR in relation to the patient's respiratory minute volume, with increasing FGFRs in VIC systems diluting the anaesthetic circuit concentration (Cust ; Wagner & Bednarski ; White & Royston ; Wright et al. ). The delivered concentration of sevoflurane increased as the vaporizer temperature increased, again as expected for vaporizers that are not temperature compensated (Patel & Goa ; Smith ; Young et al.…”

Section: Discussionmentioning

confidence: 99%

Delivery of sevoflurane to dogs using a Stephens anaesthetic machine

Ferguson

Filippich

Keates

2014

Veterinary Anaesthesia and Analgesia

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Section: Discussionmentioning

confidence: 99%

Delivery of sevoflurane to dogs using a Stephens anaesthetic machine

Ferguson

Filippich

Keates

2014

Veterinary Anaesthesia and Analgesia

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“…Mapleson 11 and White 12 described high concentrations of agent when using a VOC with low FGF. With continuous and accurate monitoring of anaesthetic concentration, however, the safety of VIC techniques has improved significantly as has shown by multiple authors [1][2][3][4][5][6][7][8] .…”

Section: Discussionmentioning

confidence: 99%

“…The use of a draw-over vaporiser positioned in-circuit (VIC) has been well described [1][2][3][4][5][6] , but when controlled ventilation is used there are significant concerns about the risk of an unpredictable output leading to overdose. Most VIC and low-flow studies have been done using Komesaroff or Goldman vaporisers.…”

mentioning

confidence: 99%

Evaluation of an Oxford Miniature Vaporizer Placed in-Circuit during the Maintenance Phase of Low-Flow Anaesthesia

Beck

Boesel²,

Seppelt

2008

Anaesth Intensive Care

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The aim of the study was to assess Oxford Miniature Vaporizer output when mounted in-circuit during the maintenance phase of anaesthesia, using isoflurane, controlled ventilation and a fresh gas flow rate less than 1 l/min. Twenty patients of ASA Physical Status I and II were recruited from routine general surgical lists. All patients were paralysed and ventilated. An out-of-circuit isoflurane vaporiser was used during the induction period (first 20 to 30 minutes). Anaesthesia was maintained using an Oxford Miniature Vaporizer placed in-circuit, using a fresh gas flow of 500 ml/min. The end-tidal isoflurane concentration was recorded for 90 minutes at five-minute intervals using a sidestream agent analyser. Two groups were compared, with the Oxford Miniature Vaporizer dial setting at either the 0.5 mark (low output setting) or at the 1.0 mark (higher output setting).At a dial setting of 0.5, the Oxford Miniature Vaporizer produced a steady end-tidal isoflurane of 0.63% (95% confidence interval 0.60 to 0.66). However, when the dial was turned to 1.0 the output was almost always excessive and had to be reduced.These findings indicate that a stable, predictable and clinically useful output can be achieved when the Oxford Miniature Vaporizer is positioned in-circuit using low-flow and controlled ventilation.

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“…For the above reasons, together with the inaccuracy of in‐circle vaporisers, the Komesaroff machine has been considered unsafe for anaesthetising mechanically ventilated patients. However, the performance of Komesaroff vaporisers delivering halothane (Bewley and others 1998), isoflurane (Bewley and others 1998, Brosnan and others 1998, Wright and others 1998) and sevoflurane (Dhara and Liu 2000) has been evaluated in human patients subjected to mechanical ventilation, and it was concluded that patients could be anaesthetised reliably and safely provided that the anaesthetic concentrations were monitored continuously. No similar studies have been carried out in dogs.…”

mentioning

confidence: 99%

Mechanical ventilation of six dogs anaesthetised with isoflurane or sevoflurane delivered by a Komesaroff anaesthetic machine

2009

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After intravenous induction, six beagles were connected to a Komesaroff machine provided with a single in-circuit vaporiser and ventilated mechanically at either nine or 14 breaths/minute while anaesthetised with either isoflurane or sevoflurane. The vaporiser was initially set at position 4/4 (fully open) and the anaesthetic concentrations were measured after one and five minutes; the vaporiser was then set at the lowest setting able to maintain anaesthesia. Cardiorespiratory variables were measured throughout the study. In most cases anaesthesia was maintained at setting 1/4 with isoflurane and at setting 1.5/4 or 2/4 with sevoflurane.

show abstract

Controlled ventilation using isoflurane with an in‐circle vaporiser

Cited by 12 publications

References 7 publications

Delivery of sevoflurane to dogs using a Stephens anaesthetic machine

Delivery of sevoflurane to dogs using a Stephens anaesthetic machine

Evaluation of an Oxford Miniature Vaporizer Placed in-Circuit during the Maintenance Phase of Low-Flow Anaesthesia

Mechanical ventilation of six dogs anaesthetised with isoflurane or sevoflurane delivered by a Komesaroff anaesthetic machine

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