Container production has increased rapidly in many parts of the U.S. over the past 15 years. Container production has been the fastest growing sector in the nursery industry and the growth is expected to continue. Weed growth in container-grown nursery stock is a particularly serious problem, because the nutrients, air, and water available are limited to the volume of the container. The extent of damage caused by weeds is often underestimated and effective control is essential. Various researchers have found that as little as one weed in a small (1 gal) pot affects the growth of a crop. However, even if weeds did not reduce growth, a container plant with weeds is a less marketable product than a weed-free product. Managing weeds in a container nursery involves eliminating weeds and preventing their spread in the nursery, and this usually requires chemical controls. However, chemical controls should never be the only management tools implemented. Maximizing cultural and mechanical controls through proper sanitation and hand weeding are two important means to prevent the spread and regeneration of troublesome weeds. Cultural controls include mulching, irrigation methods (subirrigation), and mix type. Nursery growers estimate that they spend $500 to $4000/acre of containers for manual removal of weeds, depending on weed species being removed. Economic losses due to weed infestations have been estimated at approximately $7000/acre. Reduction of this expense with improved weed control methodologies and understanding weed control would have a significant impact on the industry. Problems associated with herbicide use in container production include proper calibration, herbicide runoff concerns from plastic or gravel (especially when chemicals fall between containers) and the need for multiple applications. As with other crops, off-site movement of pesticides through herbicide leaching, runoff, spray drift, and non-uniformity of application are concerns facing nursery growers. This article reviews some current weed control methods, problems associated with these methods, and possible strategies that could be useful for container nursery growers.