Convenient One Pot Synthesis of Some Fluoroquinolones in Aqueous Media

A remarkably efficient double crossed aldol condensation of piperidin-4-one with various aromatic aldehydes is described at room temperature in the presence of diethylamine and lithium perchlorate under solvent-free conditions. Excellent yields of 3,5-bis(arylmethylidene)piperidinones are achieved in a facile one-pot general procedure. Structure of the products is determined by spectroscopic methods and elemental analysis.

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Synthesis and Structural Elucidation of Novel Bisarylmethylidenes of Cyclic Enones

Abaee

Mojtahedi

Zahedi

et al. 2007

Synthetic Communications

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Convenient One Pot Synthesis of Some Fluoroquinolones in Aqueous Media

Cited by 3 publications

References 13 publications

A highly efficient method for solvent‐free synthesis of bisarylmethylidenes of pyranones and thiopyranones

A highly efficient method for solvent‐free synthesis of bisarylmethylidenes of pyranones and thiopyranones

A highly efficient method for solvent‐free synthesis of bis(arylmethylidene)piperidinones

Synthesis and Structural Elucidation of Novel Bisarylmethylidenes of Cyclic Enones

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