Conventional Ordinary and PRP in Management of Diabetic Foot Ulcer- A Comparative Study

Abstract

Background: Diabetes mellitus is a clinical syndrome characterized by hyperglycemia caused by absolute or relative deficiency of insulin. The present study was conducted to compare PRP and conventional dressing in management of diabetic foot ulcer. Subjects and Methods: The present study was conducted on 120 patients with diabetic foot ulcers. Patients were divided into 2 groups of 60 each. Group I was those who received conventional dressing and group II patients received PRP dressings. Patients were examined and recalled regularly to see effect of dressing and size of the lesions. Results: Common site was mid foot seen in 35 and 30 in group II, fore foot seen 20 in group I and 18 in group II, hind foot seen 5 in group I and 12 in group II. The difference was non-significant (P> 0.05). At 0 week mean size of DFU was 4.2 mm in group I and 4.1 mm in group II, at 1 week was 4.0 mm in group I and 3.8 mm in group II, at 3rd week was 3.6 mm in group I and 2.4 mm in group II and 2.6 mm in group I and 1.2 mm in group II. The difference was significant (P< 0.05). Conclusion: Platelet rich plasma was effective in the management of diabetic foot ulcer. There was comparatively increase in size reduction in PRP group than conventional group.