Empowering students to learn through ICT is seen as a way to address the growing awareness and demand for preparing students to effectively participate in the emerging global knowledge economy. It is believed that, in order to maintain competitiveness in a global economy, traditional classroom practices must be re-conceptualized in a way that enables students to engage themselves in knowledge building, to become more self-directed, and to assume greater autonomy and social responsibility over their own learning. In this article, we report a case study on the use of Tablet PCs to support teaching and learning in a primary school in Hong Kong, and provide insights into how schools can harness and capitalize on the opportunities offered by such emerging technologies.