Conversion of a commercial gas chromatography-mass spectrometer to a liquid chromatography-particle beam/glow discharge mass spectrometer

Atomic Spectroscopy

“…Several other authors applied the ELCAD or developed different types of source designs for liquid analysis. ,,,,− Shekhar et al applied the ELCAD in combination with OES as a simple, rapid, and sensitive method for the determination of mercury in hepatitis-B vaccine . The accuracy of the results was within 2–9%, the analytical precision was 2–5%, and the detection limits were found to be 25 ng mL –1 .…”

“…Finally, Marcus and co-workers published some interesting work on liquid analysis. − In ref , a commercially available gas chromatography mass spectrometer (GC/MS) was converted into a liquid chromatography particle beam (LC-PB) GDMS system. The nebulization characteristics as well as the GD source temperature and plasma conditions were optimized relative to caffeine (test compound) responses, and the optimized conditions were comparable to similar work performed earlier by the authors.…”

Atomic spectrometry update. Industrial analysis: metals, chemicals and advanced materials

“…In a different approach adopted by Quarles and colleagues, a commercial GC-MS instrument has been converted to an LC-MS with a particle beam/glow discharge MS system. 117 As with the previous paper, caffeine was used as a test compound. A momentum separator removed the solvent or helium molecules, leaving solvent or carrier gas-free analyte molecules to enter the GD source.…”