Coordination Modes of a Schiff Base Derived from Substituted 2‐Aminothiazole with Chromium(III), Manganese(II), Iron(II), Cobalt(II), Nickel(II) and Copper(II) Metal Ions: Synthesis, Spectroscopic and Antimicrobial Studies

Thakar, A. S.; Joshi, K. T.; Pandya, K. S.; Pancholi, A. M.

doi:10.1155/2011/282061

Cited by 13 publications

(12 citation statements)

References 16 publications

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“…These data suggested that these complexes were ionic in nature and they were 1:1 electrolytes. The Fe (III) complex had a molar conductivity value of 105.90 Ω −1 mol −1 cm 2 , which suggested that this complex was ionic in nature and it was a 1:2 electrolyte …”

Section: Resultsmentioning

confidence: 99%

Transition metal complexes of Schiff base ligand based on 4,6‐diacetyl resorcinol

Mahmoud

Omar

Ahmed

2020

Applied Organom Chemis

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Novel Schiff base ligand based on the condensation of 4,6‐diacetyl resorcinol with 2‐amino‐4‐methylthiazole in addition to its metal complexes with Cr (III), Mn (II), Fe (III), Co (II), Ni (II), Cu (II), Zn (II) and Cd (II) ions have been synthesized. The structure, electronic properties, and thermal behaviour of Schiff base and its metal complexes have been studied by elemental analysis, mass, 1H NMR, IR spectra, thermal analysis, and theoretically by density function theory. The ligand acted as mononegative bidentate (NO) ligand and all complexes showed octahedral geometry except Cu (II) showed tetrahedral geometry as indicated from the spectral and magnetic studies. The Cu (II), Zn (II) and Cd (II) complexes were non electrolytes while the rest of the complexes were electrolytes. The antibacterial plus anticancer activities of the parent Schiff base and its metal complexes were screened. In addition, the molecular docking study was performed to explore the possible ways for binding to Crystal Structure of Human Astrovirus capsid protein (5ibv) receptor.

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Section: Resultsmentioning

confidence: 99%

Transition metal complexes of Schiff base ligand based on 4,6‐diacetyl resorcinol

Mahmoud

Omar

Ahmed

2020

Applied Organom Chemis

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“…Amino acids and its derivatives can have some extent ligand due to their good solubility properties and biological transports. Among amino acids, histidine is very significant bioactive amino acid with plentiful physiological functions and the tendency to take on interaction with proteins [7, 8, 9, 10]. They can probably to form Schiff bases at beyond their isoelectric point with 4-aminoantipyrine derivatives.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical behavior, structural, morphological, Calf Thymus-DNA interaction and in-vitro antimicrobial studies of synthesized Schiff base transition metal complexes

Palanimurugan¹,

Dhanalakshmi²,

Selvapandian³

et al. 2019

Heliyon

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New tetradentate Schiff base transition metal complexes have been derived from salicylidene-4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one and histidine were characterized by CHN analysis, magnetic susceptibility measurements, molar conductance, FAB-MS, IR, 1 H-NMR, UV, CV, EPR, Fluorescence emission, AFM and Powder XRD techniques. AFM images and Powder XRD data endure that the complexes are nano-size grains with polycrystalline structure. The spectral evidences showed that all the metal chelates are square planar geometry except [VOL] complex which exist square-pyramidal geometry. Electrochemical data (CV) for [CuL] and [VOL] complexes in acetonitrile solution indicates that the redox potential of metal ions is affected by the coordinated ligand. Electron Spin Resonance (ESR) spectra of [CuL] and [VOL] complexes were well coinciding with proposed geometries and other reported complexes. CT-DNA interaction studies of [CuL] complex reveals that an intercalation binding mode occurs between complex and DNA base pairs. The in vitro antimicrobial activity of complexes has been tested against the growth of some fungal and bacterial species persist that chelates have better control than ligand.

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“…These two mixtures were mixed and reflux with stirring for 10hrs. [22,23]. The mixture was cooled to room temperature and pour into crushed ice.…”

Section: Synthesis Of the Schiff Base Benzil-4aminoantipyrinementioning

confidence: 99%

Metal Pharmacologically Active Agents: Mode of New Tridentate Glycine amino acid with diketone (Benzil) and 4- Amino antipyrine Complexes

Ahmed

2021

Egypt. J. Chem.

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The paper presents the synthesis of complex combinations of Co(II), Ni(II), Cu(II), and Cd(II) with Schiff base obtained by the condensation reaction of 4-aminoantipyrine with benzil (diketone) and glycine amino acid. All complexes via direct reactions of metal ions with ligand in (1:2) molar ratio respectively. These complexes have been characterized via a variety of physiochemical techniques include elemental analyses (CHN), 1 H-NMR, (IR), (UV-Vis), molar conductance, magnetic moment measurement, thermal gravimetric analysis (TGA), XRD, and computational chemistry. Infrared spectra; shows that the ligand behaves as a tridentate ligand and is coordinated through N, N, O as a donor atoms sequence towards the metal ions. Consequently, all the complexes showed octahedral shapes. Finally, the synthesized Schiff base and metal complexes were screened for their biological activity against bacterial species,one gram-positive bacteria (Staphylococcus aureus), and three gram-negative bacteria Pseudomonas aereuguinosa, Escherichia coli, and Klebsiella pneumonia. These compounds show the different activity of inhibition on the growth of the bacteria respectively.

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Coordination Modes of a Schiff Base Derived from Substituted 2‐Aminothiazole with Chromium(III), Manganese(II), Iron(II), Cobalt(II), Nickel(II) and Copper(II) Metal Ions: Synthesis, Spectroscopic and Antimicrobial Studies

Cited by 13 publications

References 16 publications

Transition metal complexes of Schiff base ligand based on 4,6‐diacetyl resorcinol

Transition metal complexes of Schiff base ligand based on 4,6‐diacetyl resorcinol

Electrochemical behavior, structural, morphological, Calf Thymus-DNA interaction and in-vitro antimicrobial studies of synthesized Schiff base transition metal complexes

Metal Pharmacologically Active Agents: Mode of New Tridentate Glycine amino acid with diketone (Benzil) and 4- Amino antipyrine Complexes

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