COPD in farmers: what have we learnt?

Elliott, Leslie; Essen, Susanna G. Von

doi:10.1183/13993003.01768-2015

Cited by 5 publications

(3 citation statements)

References 25 publications

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“…All these toxic sprays used in fields are unfortunately inhaled by the farmers which directly contributes to the development of COPD in farmers. A study by Elliot et al has concentrated on the environmental exposure causing COPD whereas our study has observed that 26.66% of farmers acquired COPD due to ample use of toxic sprays in farms which are inhaled by farmers continuously [22].…”

Section: Discussioncontrasting

confidence: 51%

Environmental Exposures and Phenotype of Non-smoking COPD

Arbat¹,

Arbat²,

Agrawal³

et al. 2022

Preprint

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Chronic obstructive pulmonary disease (COPD) is strongly associated with tobacco smoking and it is the increasing cause of morbidity and mortality worldwide. The prevalence of COPD among never smokers varies widely across regions, areas, and nations. COPD in smokers has been extensively explored worldwide, however, COPD in non-smokers is under-explored and there is limited data available on non-smoking COPD. We determined the role of environmental pollution and biomass fuel exposure in COPD patients who were non-smokers. We evaluated the clinical profile of non-smokers with COPD in a retrospective observational study. 180 non-smoker COPD patients were selected from the year 2016-to 2018. We found that many patients with COPD are non-smokers and the incidence is higher among the rural population, suggesting that non-smoking COPD is evolving rapidly due to biomass smoke and other environmental pollutant exposures.

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Section: Discussioncontrasting

confidence: 51%

Environmental Exposures and Phenotype of Non-smoking COPD

Arbat¹,

Arbat²,

Agrawal³

et al. 2022

Preprint

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“…A cross-sectional survey in France found that only 2.9% of crop farmers had COPD (23), a figure much lower than those from other studies in European farmers mainly working on livestock farms where the reported COPD prevalence ranged between 10.7% and 30.2%. (24) It is also interesting that our findings suggest a relatively high prevalence of a restrictive spirometric pattern (10.3%) among villagers. Currently, the determinants of restrictive spirometry pattern remain poorly understood; explanations might include genetic factors or some adverse early life exposures impacting on childhood development.…”

Section: Discussionmentioning

confidence: 50%

Farming, pesticide exposure and respiratory health: a cross-sectional study in Thailand

et al. 2021

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ObjectiveTo assess the association of lung function and respiratory symptoms with farming, particularly pesticide use, in an agricultural province in Thailand.MethodsWe undertook a cross-sectional survey of adults aged 40–65 in Nan province, Thailand, between May and August 2019. We randomly recruited 345 villagers and enriched the sample with 82 government employees. All participants performed post-bronchodilator spirometry and completed a questionnaire covering information on respiratory symptoms, farming activities, pesticide use and known risk factors for respiratory disease. Associations of respiratory outcomes with farming and pesticide exposures were examined by multivariable regression analysis.ResultsThe response rate was 94%. The prevalence of chronic airflow obstruction among villagers was 5.5%. Villagers had, on average, a lower percent predicted post-bronchodilator forced expiratory volume in one second/forced vital capacity (FEV1/FVC) than government employees (98.3% vs 100.3%; p=0.04). There was no evidence of association of lung function with farming activities, the use of specific herbicides (glyphosate and paraquat), insecticides (organophosphates and pyrethroids) or fungicides. The exceptions were poultry farming, associated with chronic cough and an increase of FEV1/FVC, and atrazine, for which duration (p-trend <0.01), intensity (p-trend <0.01) and cumulative hours (p-trend=0.01) of use were all associated with higher FEV1/FVC in an exposure–response manner. Cumulative hours (−280 mL/hour), low duration (−270 mL/year) and intensity (−270 mL/hour/year) of atrazine use were associated with lower FVC.ConclusionsChronic airflow obstruction is uncommon among villagers of an agricultural province in Nan, Thailand. Farming and pesticide use are unlikely to be major causes of respiratory problems there.

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“…Moreover, health disparities in the United States are seen among minorities and immigrants who account for the majority of seasonal farm workers frequently exposed to PM in agricultural dusts (2,3). Strikingly, many farm workers live below the poverty level with limited access to healthcare services thus increasing their risk of developing respiratory disorders from exposure to airborne pollutants (4)(5)(6)(7). Most air pollution is man-made and derived from fossil fuels including toxins from car exhaust and industrial waste (8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

Every breath you take: Impacts of environmental dust exposure on intestinal barrier function–from the gut-lung axis to COVID-19

Crawford

Nordgren

McCole

2021

American Journal of Physiology-Gastrointestinal and Liver Physi

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As countries continue to industrialize, major cities experience diminished air quality, while rural populations also experience poor air quality from sources such as agricultural operations. These exposures to environmental pollution from both rural and populated/industrialized sources have adverse effects on human health. Although respiratory diseases (e.g. asthma and chronic obstructive pulmonary disease) are the most commonly reported following long-term exposure to particulate matter and hazardous chemicals, gastrointestinal complications have also been associated with the increased risk of lung disease from inhalation of polluted air. The interconnectedness of these organ systems has offered valuable insights into the roles of the immune system and the micro/mycobiota as mediators of communication between the lung and the gut during disease states. A topical example of this relationship is provided by reports of multiple gastrointestinal symptoms in patients with coronavirus disease 2019 (COVID-19), while the rapid transmission and increased risk of COVID-19 has been linked to poor air quality and high levels of particulate matter. In this review, we focus on the mechanistic effects of environmental pollution on disease progression with special emphasis on the gut-lung axis.

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COPD in farmers: what have we learnt?

Cited by 5 publications

References 25 publications

Environmental Exposures and Phenotype of Non-smoking COPD

Environmental Exposures and Phenotype of Non-smoking COPD

Farming, pesticide exposure and respiratory health: a cross-sectional study in Thailand

Every breath you take: Impacts of environmental dust exposure on intestinal barrier function–from the gut-lung axis to COVID-19

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