Copper/Cuprous Oxide Nanoparticles Decorated Reduced Graphene Oxide Sheets Based Platform for Bio‐Electrochemical Sensing of Dopamine

Abstract

A rudimentary simple sonochemical approach has been employed for the synthesis of copper/cuprous oxide nanoparticles (Cu/Cu2O NPs) decorated graphene oxide (GO) sheets. Simply, an aqueous dispersion of GO was sonochemically treated with Cu/Cu2O NPs as obtained through a simple electrochemical dissolution method to get the Cu/Cu2O/rGO nanocomposite. The decoration of Cu/Cu2O NPs on GO sheets resulted in the excellent sensing activity of Cu/Cu2O/rGO nanocomposite towards dopamine in the pharmaceutical formulation at the electrode interface due to enhanced electron mobility in GO sheet and high catalytic activity of Cu/Cu2O NPs. The comparison has been laid out based on various characterization techniques viz. powder X‐ray diffraction (PXRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infra‐red (FTIR) spectroscopy and Raman spectroscopy. The fabricated sensor depicted high sensitivity of 0.806 μA/μM for dopamine in a broad linear range of 0.25 –17 μM. Moreover, the remarkable detection limit of 2.6 nM was found for dopamine, and the developed sensor exhibited a wide separation ca. 140 mV between the respective detection peaks of dopamine and uric acid, which is a major interferent in the analysis of dopamine.

Synergistic effect of pistachio shell powder and nano-zerovalent copper for chromium remediation from aqueous solution

“…Various nanomaterials studied for Cr(VI) remediation include nZVI (Sharma et al 2009), MnO2 (Dinh et al 2020), ZnO (Le et al 2019), TiO2 (Gopinath et al 2020), Fe2O3 (Li et al 2019, and their variants with other metal/metal oxides and chalcogenides (Karimi-Maleh et al 2020;Peng and Guo 2020;Zhao et al 2019). Recently Cu/Cu2O nanoparticles have found application in electrochemical sensing (Devnani et al 2019;Li et al 2018) and adsorption of heavy metal (Iqbal et al 2019). Cu/Fe bimetallic nanocomposite materials have been found suitable for remediation of Cr(VI) (Jia et al 2019;Jiang et al 2018;Qu et al 2021;Zhu et al 2016;Zhu et al 2018), but very few literature reports are known for utilization of zerovalent copper as Cr(VI) adsorbent (Li et al 2015a;Wu et al 2009).…”

An Unsymmetrical Perylene Diimide Dye Modified Carbon Felt Electrode as A Novel Electrochemical Platform for Dopamine Detection

“…[1] Also, higher amounts of dopamine in the body may be an indicator for diseases like Alzheimer's, Parkinson's, schizophrenia, epilepsy and attention deficit hyperactivity disorder. [1][2][3][4] It has also been known that this molecule is in cationic form and can be found in the body fluids and brain tissues. [1] Besides being a neurotransmitter, dopamine can also be used as medicine for treatment i. e. of bradycardia and hypotension.…”

“…[1] For overwhelming these drawbacks, new strategies like centri-voltammetry [7] have been developed or various electrode modification techniques have been applied. [1][2][3][4]6,8] Perylene and perylene derivatives have been known to possess enhanced absorption coefficient, high fluorescence quantum yield and better stability in terms of chemical, thermal and photochemical reactions. The other significant property of perylene derivatives is their high charge transfer properties which pave the way for enhanced electrochemical properties.…”

“…Dopamine is a neurotransmitter that has fundamental aspects in central nervous, cardiovascular and hormonal systems . Also, higher amounts of dopamine in the body may be an indicator for diseases like Alzheimer's, Parkinson's, schizophrenia, epilepsy and attention deficit hyperactivity disorder . It has also been known that this molecule is in cationic form and can be found in the body fluids and brain tissues .…”

“…Moreover, the products that are obtained after the oxidation of these compounds can be accumulated on the electrode surface causing damages like decrease in sensitivity and reproducibility . For overwhelming these drawbacks, new strategies like centri‐voltammetry have been developed or various electrode modification techniques have been applied …”