Copper(I)/(II) or silver(I) ions towards 2-mercaptopyrimidine: An exploration of a chemical variability with possible biological implication

The Importance of Heterolepticity in Improving the Antibacterial Activity of Bismuth(III) Thiolates

“…While many metal complexes containing the neutral PYM(H) ligand have been structurally characterised, only one complex containing the anionic PYM ligand has been characterised . The only antibacterial studies associated with metal complexes of this ligand in any form were performed on a series of Cu and Ag complexes of form [M(PPh 3 ) n {PYM(H)} m ]X (M = Cu; X = BF 4 ; n = 3, m = 1; n = m = 2M = Ag; X = NO 3 ; n = 3, m = 1; n = 2, m = 1) . The Ag complexes were more active towards S. aureus than the Cu complexes (8.0 vs. 24 µg/mL), and their activities were similar to that of complex 2 (5.0 µg/mL).…”

[Cu(POP)(N^S)][PF6] and [Cu(xantphos)(N^S)][PF6] compounds with 2-(thiophen-2-yl)pyridines

“…We recently reported a series of [Cu(P^P)(N^S)][PF 6 ] complexes with P^P ¼ bis(2-(diphenylphosphino)phenyl)ether (POP) or 4,5bis(diphenylphosphino)-9,9-dimethylxanthene (xantphos) (Scheme 1) and N^S being a 2-(alkylthio)pyridine. 23 These investigations were prompted by the fact that several previously reported copper(I) complexes combining heterocyclic thioamide and phosphane ligands are emissive 24,25 as is [Cu 2 (dppdtbpf) 2 (m-NCS) 2 ] (dppdtbpf ¼ 1-diphenylphosphino-1 0 -di-tert-butylphosphinoferrocene). 26 Like [Cu(P^P)(N^N)] + complexes, 3 those with a [Cu(P^P)(N^S)] + composition exhibit partitioning of the characters of the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) such that the HOMO has dominant copper character with smaller contributions from the ligands and the LUMO is localized on the N^S ligand.…”

Softening the Donor-Set: From [Cu(P^P)(N^N)][PF6] to [Cu(P^P)(N^S)][PF6]

“…A number of [Cu(PPh3)2(N^S)] and related compounds, in which H(N^S) is a thiosemicarbazone, have been described [16][17][18][19][20], and there are several reports of thiocyanato-bridged dicopper(I) compounds, for example [Cu2(PPh3)2(2-Mepy)2(μ-NCS)2] [21], which present a distorted tetahedral CuP2NS coordination sphere. Copper(I) complexes incorporating heterocyclic thioamide and phosphane ligands have also been described [22,23], and are shown to exhibit broad emission bands in the range λ em max = 490-495 nm (λexc = 270-291 nm) [21].…”

“…, which present a distorted tetahedral CuP 2 NS coordination sphere. Copper(I) complexes incorporating heterocyclic thioamide and phosphane ligands have also been described [22,23], and are shown to exhibit broad emission bands in the range λ em max = 490-495 nm (λ exc = 270-291 nm) [21]. [Cu 2 (dppdtbpf) 2 (µ-NCS) 2 ] (dppdtbpf = 1-diphenylphosphino-1 -di-tert-butylphosphinoferrocene) exhibits a broad emission with λ em max ≈ 500 nm assigned to a metal-centered transition [24].…”