Copper(iii) Dithiocarbamates

Victoriano, Luis I.; Granifo, Juan; Parraguez, Laura

doi:10.4067/s0366-16442000000300020

Cited by 3 publications

(4 citation statements)

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“…In theory they should be amenable to study by NMR spectroscopy but in practice this can be complicated by the presence of small amounts of copper(II) complexes. Addition of thiuram disulfides to CuCl 2 [26] or reaction of thionyl chloride with [Cu(S 2 CNR 2 ) 2 ] [75] affords copper(III) dichloride complexes [CuCl 2 (S 2 CNR 2 )] akin to the gold(III) complexes utilized in cancer therapy [76,77]. Related dibromo complexes are also known [26] but none of these have been studied by X-ray crystallography so the precise molecular structures remain unknown.…”

Section: Copper Chemistrymentioning

confidence: 98%

“…Addition of thiuram disulfides to CuCl 2 [26] or reaction of thionyl chloride with [Cu(S 2 CNR 2 ) 2 ] [75] affords copper(III) dichloride complexes [CuCl 2 (S 2 CNR 2 )] akin to the gold(III) complexes utilized in cancer therapy [76,77]. Related dibromo complexes are also known [26] but none of these have been studied by X-ray crystallography so the precise molecular structures remain unknown. Given the commensurate nature of the squareplanar CuS 4 centers in copper(II) and copper(III) bis(dithiocarbamate) complexes it is perhaps not surprising that mixed-valence copper(II)-copper(III) complexes are accessible [70].…”

Section: Copper Chemistrymentioning

confidence: 98%

“…This requires that the starting metal centre be readily oxidized and often (but not always) ends up with the incorporation of two dithiocarbamate ligands. An example is the addition of thiuram disulfides to CuCl 2 which affords copper(III) complexes [Cl 2 Cu(S 2 CNR 2 )] [26]. A third route which has more limited applicability is the insertion of carbon disulfide into pre-formed metal-amide functionality (eq.…”

Section: Synthesismentioning

confidence: 99%

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Metal-dithiocarbamate complexes: chemistry and biological activity

Hogarth¹

2012

MRMC

255

157

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Dithiocarbamates are highly versatile mono-anionic chelating ligands which form stable complexes with all the transition elements and also the majority of main group, lanthanide and actinide elements. They are easily prepared from primary or secondary amines and depending upon the nature of the cation can show good solubility in water or organic solvents. They are related to the thiuram disulfides by a one-electron redox process (followed by dimerisation via sulfur-sulfur bond formation) which is easily carried out upon addition of iodide or ferric salts. Dithiocarbamates are lipophilic and generally bind to metals in a symmetrical chelate fashion but examples of other coordination modes are known, the monodentate and anisobidentate modes being most prevalent. They are planar sterically non-demanding ligands which can be electronically tuned by judicious choice of substituents. They stabilize metals in a wide range of oxidation states, this being attributed to the existence of soft dithiocarbamate and hard thioureide resonance forms, the latter formally resulting from delocalization of the nitrogen lone pair onto the sulfurs, and consequently their complexes tend to have a rich electrochemistry. Tetraethyl thiuramdisulfide (disulfiram or antabuse) has been used as a drug since the 1950s but it is only recently that dithiocarbamate complexes have been explored within the medicinal domain. Over the past two decades anti-cancer activity has been noted for gold and copper complexes, technetium and copper complexes have been used in PET-imaging, dithiocarbamates have been used to treat acute cadmium poisoning and copper complexes also have been investigated as SOD inhibitors.

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Section: Copper Chemistrymentioning

confidence: 98%

Section: Copper Chemistrymentioning

confidence: 98%

Section: Synthesismentioning

confidence: 99%

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Metal-dithiocarbamate complexes: chemistry and biological activity

Hogarth¹

2012

MRMC

255

157

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“…In a biological study it was observed that thiram reacts with copper and lead metals to enhance the uptake of these metals by the roots of the plants while titanium and vanadium tend to reduce the thiram as a ligand to dithiocarbamates. 3,4 Complexes of thiodicarbonic diamide silver and mercury derivatives ( 5 The use of these ligands as complexes with IIB metals, to form precursors for II-VI semiconductor nanoparticles has attracted some interest, due to the presence of sulphur atoms. The thiuram disulphide unit consists of four sulfides and hence the binding to the metal centre upon formation of complexes would be through the sulfides.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Precursor Concentration, Temperature and Capping Group on the Morphology of CdS Nanoparticles

Moloto¹,

Revaprasadu²,

Pl³

et al. 2009

j nanosci nanotechnol

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A novel ligand to the synthesis of nanoparticles has been employed in this study. A Tetramethylthiuram disulphide cadmium complex (abundant in sulphur atoms) was used as a single-source precursor for the synthesis of CdS nanoparticles. The CdS nanoparticles were synthesized under various conditions and were characterized using UV/Vis, PL, XRD and TEM. The influence of the precursor concentration, temperature and capping environment as factors affecting the morphology and size of the nanoparticles was investigated. We observed that with an increase in precursor concentration, there was an increase in particle sizes and the morphology evolved from spherical to rod-shaped nanoparticles. An increase in temperature showed only evidence of increasing the particle sizes whilst the capping environment had a profound influence on the morphology of the nanoparticles. The work reported in this paper demonstrate that factors such as temperature, concentration and the capping group affects the growth of nanoparticles either in size and/or shape.

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