Cord Leptin is Associated with Neuropsychomotor Development in Childhood

Karakosta, Polyxeni; Margetaki, Katerina; Fthenou, Eleni; Kampouri, Mariza; Kyriklaki, Andriani; Koutra, Katerina; Chalkiadaki, Georgia; Roumeliotaki, Theano; Vafeiadi, Marina; Kogevinas, Manolis; Mantzoros, Christos S.; Chatzi, Lida

doi:10.1002/oby.22571

Cited by 3 publications

(3 citation statements)

References 43 publications

(66 reference statements)

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“…For measuring the neurodevelopmental outcomes standardized and validated tests should be considered according to the age of the target group. Exemplarily named might be the Bayley Scales of Infant and Toddler Development, Third Edition [210], the McCarthy Scale of Children’s Abilities (MCSA) [211], or Raven’s Coloured Progressive Matrices and Trail Making Tests [212] as exemplarily described and applied by Karakosta et al [213], SETK 3-5 [192], PACST [199], amongst others.…”

Section: Discussionmentioning

confidence: 99%

Recommendation of Neurorehabilitation according to the Padovan-Method Neurofunctional Reorganization® for Treating Neurodevelopmental Disorders: A Systematic Review

Vogel¹,

Ostermann²,

Vogel³

et al. 2022

Complement Med Res

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Objective: The PADOVAN-METHOD NEUROFUNCTIONAL REORGANI¬SATION® is a promising approach in speech therapy treating neuro¬developmental disorders with traumatic or congenital origin. Its use is based on a long-time experience of certified therapists. However, its efficacy and safety has not been assessed in a systematic review. This report aims to gain evidence for the use of the therapy method. Methods and analysis: Guidelines of PRISMA, the Cochrane Collaboration Handbook, MECIR and GRADE were followed. General databases (Cochrane Library, PubMed, AWMF, Anthromedics, etc.) and further 38 databases including grey literature were searched. Hand search was done additionally and contact to experts used to retrieve unpublished manuscripts. All trials investigating the effect of the method in comparison to either no intervention, alternative as state of the art or placebo intervention in English, Portuguese and German language were included. No restriction regarding study design was applied. Data related to the intervention outcome and the study method was extracted and analysed idependently. Risk of Bias was assessed using ROBINS-I for non-RCTs, adherence to CARE-Guidelines was analysed for case series or reports and keeping the Declaration of Helsinki was checked for all items. Results are presented both in evidence profiles and summary of findings tables according to GRADE. Results: Amongst 98 records assessed for eligibility, four studies and 14 case reports were identified with a total of n = 196 participants. Duration of reported interventions was between two days and two years. Microcephalia, down-syndrome, unspecified neurological disorders and myo-functional disorders were main conditions of the patients with neurodevelopmental disorders. Only indirect overlapping of operationalised criteria was found. Conclusions are therefore limited. Conclusion: The Padovan-Method® is a holistic therapy approach claiming its feasibility to a large group of disorders making a proof of efficacy difficult. An application of therapy according to the Padovan-Method® by trained therapists might be considered by clinicians (weak recommendation) and a contribution to a relief of symptoms or improvements of condition of named conditions might be gained. Therefore, development and validation of therapy protocols and further investigation are required. PROSPERO Registration: CRD42020156124. Keywords: neurological rehabilitation, neurodevelopmental disorders, rehabilitation of speech and language disorders, systematic review

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Section: Discussionmentioning

confidence: 99%

Recommendation of Neurorehabilitation according to the Padovan-Method Neurofunctional Reorganization® for Treating Neurodevelopmental Disorders: A Systematic Review

Vogel¹,

Ostermann²,

Vogel³

et al. 2022

Complement Med Res

View full text Add to dashboard Cite

show abstract

“…In conducting up new trials, special attention should be paid to the methodological challenges in rehabilitative medicine [195]. [198] as exemplarily described and applied by Karakosta, Margetaki et al [199], SETK 3-5 [174], PACST [184] amongst others.…”

Section: Authors Conclusionmentioning

confidence: 99%

“…For measuring neurodevelopmental outcomes, standardised and validated tests should be considered according to the age of the target group. Exemplarily named might be the Bayley Scales of Infant and Toddler Development, Third Edition [196], the McCarthy Scale of Children's Abilities (MCSA) [197] or Raven's Coloured Progressive Matrices and Trail Making Tests [198] as exemplarily described and applied by Karakosta, Margetaki et al [199], SETK 3-5 [174], PACST [184] amongst others.…”

Section: Authors Conclusionmentioning

confidence: 99%

Recommendation of Neurorehabilitation according to the Padovan-Method Neurofunctional Reorganisation® for treating neurodevelopmental disorders: a systematic review

Vogel

Ostermann

Vogel

et al. 2021

Preprint

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Background: The PADOVAN-METHOD NEUROFUNCTIONAL REORGANISATION® is a promising approach in speech therapy for treating neurodevelopmental disorders of traumatic or congenital origin. Its use is based on a long-time experience of certified therapists; however, its efficacy and safety has not yet been assessed in a systematic review. This report aims to gain evidence for the use of the therapy method. Methods: Guidelines of PRISMA, the Cochrane Collaboration Handbook, MECIR and GRADE were followed. General databases (Cochrane Library, PubMed, AWMF, Anthromedics) and additional 38 databases including grey literature were searched. Hand search was also done and experts were contacted to retrieve unpublished manuscripts. All trials investigating the effect of the method in comparison to either no intervention, alternative as state of the art or placebo intervention in English, Portuguese and German language were included. No restriction regarding study design was applied. Data related to the intervention outcome and the study method was extracted and analysed idependently. Risk of Bias was assessed using ROBINS-I for non-RCTs, adherence to CARE-Guidelines was analysed for case series or reports and keeping the Declaration of Helsinki was checked for all items. Results are presented both in evidence profiles and summary of findings tables according to GRADE. Results: Amongst 98 records assessed for eligibility, and four studies and 14 case reports were identified as appropriate for analysis with a total of n = 196 participants. Duration of reported interventions was between two days and two years. Microcephalia, down-syndrome, unspecified neurological disorders and myo-functional disorders were the main conditions of the patients with neurodevelopmental disorders. Only indirect overlapping of operationalised criteria was found; therefore conclusions are limited. Conclusion: The Padovan-Method® is a holistic therapy approach claiming feasibility to a large group of disorders making proof of efficacy difficult. An application of therapy according to the Padovan-Method® by trained therapists might be considered by clinicians (weak recommendation), and a contribution to the relief of symptoms or improvements of the conditions might be gained. Therefore, development and validation of therapy protocols and further investigation are required. PROSPERO Registration: CRD42020156124.

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Prediction of cord blood leptin on infant’s neurodevelopment: A birth cohort in rural Yunnan, China

Chen

Xiao²,

Song³

et al. 2023

Psychoneuroendocrinology

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Cord Leptin is Associated with Neuropsychomotor Development in Childhood

Cited by 3 publications

References 43 publications

Recommendation of Neurorehabilitation according to the Padovan-Method Neurofunctional Reorganization® for Treating Neurodevelopmental Disorders: A Systematic Review

Recommendation of Neurorehabilitation according to the Padovan-Method Neurofunctional Reorganization® for Treating Neurodevelopmental Disorders: A Systematic Review

Recommendation of Neurorehabilitation according to the Padovan-Method Neurofunctional Reorganisation® for treating neurodevelopmental disorders: a systematic review

Prediction of cord blood leptin on infant’s neurodevelopment: A birth cohort in rural Yunnan, China

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