We describe the cone of deformations of a Coxeter permutohedron, or equivalently, the nef cone of the toric variety associated to a Coxeter complex. This class of polytopes contains important families such as weight polytopes, signed graphic zonotopes, Coxeter matroids, root cones, and Coxeter associahedra. Our description extends the known correspondence between generalized permutohedra, polymatroids, and submodular functions to any finite reflection group.