This paper presents a characteristic analysis and experimental verification for predicting the electromagnetic losses in high-speed permanent magnet synchronous motors. To predict the operating characteristics (such as speed and input current), dynamic modeling is conducted that combines models for the space vector pulse width modulation (SVPWM) inverter and high-speed permanent magnet synchronous motor (HPMSM). By applying the predicted harmonic currents to the electromagnetic analysis, DC and AC copper losses of the stator winding, and eddy current loss of the rotor sleeve and rotor permanent magnet, are comprehensively analyzed using the finite element (FE) method. In particular, by analyzing the magnetic field behavior of magnetic flux density according to harmonics, a core loss analysis technique was presented. The validity of the hybrid analysis, which combines the stator copper loss and rotor eddy current loss derived from the FE analysis and the proposed core loss analysis, was verified through comparison with the experimental results under various operating conditions. Compared with the experimental results, the error of total losses using the hybrid analysis with a sinusoidal current was about 47.39%, and total losses using the hybrid analysis with a harmonic current was significantly improved to within 3.7%.