Core needle biopsy for diagnosing lymphoma in cervical lymphadenopathy: Meta‐analysis

Warshavsky, Anton; Rosen, Ran; Perry, Chava; Muhanna, Nidal; Ungar, Omer J.; Neiderman, Narin N. Carmel; Fliss, Dan M.; Horowitz, Gilad

doi:10.1002/hed.26381

Cited by 14 publications

(18 citation statements)

References 37 publications

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“…Some studies have confirmed that lymphoma rarely occurs necrosis, usually caused by trophoblast artery embolization resulting in coagulative necrosis. CEUS can intuitively show the necrotic area in lymphoma [ 10 , 14 – 17 ], coagulative necrosis was described in the pathologic findings of lymphoma cases with intermittent specimens in this study.…”

Section: Discussionmentioning

confidence: 64%

Correlation between physical characteristics of biopsy specimen and disease of cervical lymph node after contrast-enhanced ultrasound

et al. 2022

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Background To investigate the correlation between physical characteristics and disease of cervical lymph node biopsy specimens after contrast-enhanced ultrasound. Methods All patients were biopsied after CEUS, 235 patients were divided into three groups A, B and C according to the physical characteristics of specimens: 92 patients in group A were complete tissue specimens; 113 patients in group B were discontinuous tissue specimens. There were 30 patients in group C, including a small number of tissue and floc, purulent and bloody specimens. Pathological examination, pathogen culture examination and Gene X-Pert MIB examination were completed for all patients in the three groups, and statistical analysis was conducted on the integrity and traits of the specimens. Results Group A included 92 intact tissue specimens, 21 with reactive hyperplasia, 17 with lymphoma, 12 with metastatic carcinoma, 13 with lymphadenopathy, 15 with necrotizing lymphadenitis, and rare lymphadenopathy. In group B, 113 patients were treated with intermittent tissue specimens, including infected lymph nodes, lymphoma in 1 case, metastatic carcinoma in 3 cases and sarcoidosis in 1 case. There were 30 patients in group C, including a small amount of tissue and floc, purulent and bloody specimens, all of which were infected lymph nodes. The χ2 value of malignant and benign lymph nodes was 42.401, p = 0.000. Conclusion The physical characteristics of cervical lymph node biopsy specimens after CEUS are correlated with the disease, which has guiding significance for postoperative specimen selection.

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Section: Discussionmentioning

confidence: 64%

Correlation between physical characteristics of biopsy specimen and disease of cervical lymph node after contrast-enhanced ultrasound

et al. 2022

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“…81 However, other studies have shown far lower diagnostic yield. A recent metanalysis of CNB for diagnosis of lymphoma in cervical lymphadenopathy found a rate of actionable lymphoma diagnoses as low as 30% (range 30%-96.3%) 87 and a recent study of 457 biopsies (339 excisional and 118 CNB) found that only 56.8% of CNB samples contained adequate tissue compared to 96.8% of excisional biopsy samples. 88 In this rapidly evolving field, the American Society for Clinical…”

Section: Gold Standard Sampling Technique Most Invasive and Least Ava...mentioning

confidence: 99%

The diagnosis and management of suspected lymphoma in general practice

Paquin

Oyogoa

McMurry

et al. 2022

European J of Haematology

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With rapid advancements in diagnosis and treatment of malignancies, the gap between generalists and subspecialists continues to widen, particularly in cancers like lymphoma where the spectrum of disease varies from indolent to rapidly progressive.Prior to establishing with a hematologist/oncologist, patients must be accurately and comprehensively diagnosed and managed for lymphoma in the generalist setting. In the following manuscript, we review the common clinical presentations in which should raise concern for lymphoma. We summarize the literature regarding the role of laboratory studies including complete blood count and peripheral blood flow cytometry, the recommendations for lymph node sampling, the role and selection of imaging modalities, and ideal patient monitoring for high-risk clinical syndromes that may be encountered in lymphoma.

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“…Numerous complications including bleeding, bruising, discomfort, and infection are associated with core biopsy. In spite of this, the non-availability of a surplus amount of tissue is another problem associated with this diagnosis [ 46 ].…”

Section: Reviewmentioning

confidence: 99%

Review of Head and Neck Masses in the Indian Population Based on Prevalence and Etiology With an Emphasis on Primary Diagnostic Modalities

Bhasker

2021

Cureus

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Head and neck masses are classified as sebaceous cysts (epidermoid cysts), cervical lymphadenopathy, benign lipomas, lymph nodes, thyroid swellings, or tuberculosis lymphadenitis that may be painful or painless, adherent or fluctuant. In spite of this, they have distinct prognoses and pathological features. The anatomical location of the swelling and other demographic manifestations of the patient provide valuable information about the cause and type of swelling. Computed tomography (CT), magnetic resonance imaging, positron emission tomography-CT, and ultrasonography are the gold standard imaging methods for the head and neck examination. These methods are used according to the region considered for the study. Fine-needle aspiration cytology of lymph nodes is known to be effective, simple, and sometimes the only tool for the diagnosis of lymph node malignancies. This review highlights the epidemiological aspect of head and neck masses in the Indian population.

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Core needle biopsy for diagnosing lymphoma in cervical lymphadenopathy: Meta‐analysis

Cited by 14 publications

References 37 publications

Correlation between physical characteristics of biopsy specimen and disease of cervical lymph node after contrast-enhanced ultrasound

Correlation between physical characteristics of biopsy specimen and disease of cervical lymph node after contrast-enhanced ultrasound

The diagnosis and management of suspected lymphoma in general practice

Review of Head and Neck Masses in the Indian Population Based on Prevalence and Etiology With an Emphasis on Primary Diagnostic Modalities

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