Core-shell microparticles: From rational engineering to diverse applications

Zhang, Xiaoli; Qu, Qi-Xing; Zhou, Aying; Wang, Yulin; Jian, Zhang; Xiong, Ranhua; Lenders, Vincent; Manshian, Bella B.; Hua, Dawei; Soenen, Stefaan; Huang, Chaobo

doi:10.1016/j.cis.2021.102568

Cited by 70 publications

(38 citation statements)

References 193 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…α1 receptors are mainly distributed in the vascular smooth muscle (such as skin, mucosal blood vessels, and some internal organs). − When excited, it causes vasoconstriction. α1 receptors are also distributed in the pupil dilator muscle, and the pupil dilator muscle contracts and the pupil dilates when excited . α2 receptors are mainly distributed on the presynaptic membrane of noradrenergic nerves .…”

Section: Resultsmentioning

confidence: 99%

Chiral Luminescent Sensor Eu-BTB@d-Carnitine Applied in the Highly Effective Ratiometric Sensing of Curing Drugs and Biomarkers for Diabetes and Hypertension

et al. 2022

View full text Add to dashboard Cite

Chiral drugs are of great significance in drug development and life science because one pair of enantiomers has a different combination mode with target biological active sites, leading to a vast difference in physical activity. Metal–organic framework (MOF)-based chiral hybrid materials with specific chiral sites have excellent applications in the highly effective sensing of drug enantiomers. Sitagliptin and clonidine are effective curing drugs for controlling diabetes and hypertension, while insulin and norepinephrine are the biomarkers of these two diseases. Excessive use of sitagliptin and clonidine can cause side effects such as stomach pain, nausea, and headaches. Herein, through post-synthetic strategy, MOF-based chiral hybrid material Eu-BTB@ d -carnitine (H3BTB = 1,3,5-benzenetrisbenzoic acid) was synthesized. Eu-BTB@ d -carnitine has dual emission peaks at 417 and 616 nm when excited at 330 nm. Eu-BTB@ d -carnitine can be applied in luminescent recognition toward sitagliptin and clonidine with high sensitivity and low detection limit (for sitagliptin detection, K sv is 7.43 × 106 [M–1]; for clonidine detection, K sv is 9.09 × 106 [M–1]; limit of detection (LOD) for sitagliptin is 10.21 nM, and LOD of clonidine is 8.34 nM). In addition, Eu-BTB@ d -carnitine can further realize highly sensitive detection of insulin in human fluids with a high K sv (2.08 × 106 [M–1]) and a low LOD (15.48 nM). On the other hand, norepinephrine also can be successfully discriminated by the hybrid luminescent platform of Eu-BTB@ d -carnitine and clonidine with a high K sv value of 4.79 × 106 [M–1] and a low LOD of 8.37 nM. As a result, the chiral hybrid material Eu-BTB@ d -carnitine can be successfully applied in the highly effective ratiometric sensing of curing drugs and biomarkers for diabetes and hypertension.

show abstract

Section: Resultsmentioning

confidence: 99%

Chiral Luminescent Sensor Eu-BTB@d-Carnitine Applied in the Highly Effective Ratiometric Sensing of Curing Drugs and Biomarkers for Diabetes and Hypertension

et al. 2022

View full text Add to dashboard Cite

show abstract

“…151,152 For instance, biodegradable and biocompatible polymer shell materials with dened thickness, pores, and degradation properties can act as a barrier and control the release of core compounds containing drugs and antibiotics which have been great assets in the biomedical eld. 153 In electrodes for energy storage, a hollow structure and void create a space to allow thermal or volumetric expansions caused by continuous ion insertion/de-insertions. For nanomaterial preparation, core materials serve as 'templates' for building hierarchical hollow structures.…”

Section: Hybrid Forcesmentioning

confidence: 99%

MXene in core–shell structures: research progress and future prospects

et al. 2022

View full text Add to dashboard Cite

show abstract

“…20 Functionalization as a strategy has been successfully applied to a wide-range of materials ranging from nanobubbles 21 to nanofibers 22 to core-shell microparticles. 23 For example, Gole and colleagues exploited the alkynophilicity of Pd 2+ ions to achieve a high loading of Pd nanoparticles in alkyne-functionalized MOFs, resulting in highly efficient heterogeneous catalysis. 24 While there are several strategies that can be employed for the functionalization of MOFs, the most widely used is postsynthetic modification, where the functionalization is carried out after the MOF is synthesized.…”

Section: Dhiraj Bhatiamentioning

confidence: 99%