Corneal Biomechanics in Ectatic Diseases: Refractive Surgery Implications

Ambrósio, Renato; Correia, Fernando Faria; Lopes, Bernardo; Salomão, Marcella Q.; Luz, Allan; Dawson, Daniel G.; Elsheikh, Ahmed; Vinciguerra, Riccardo; Vinciguerra, Paolo; Roberts, Cynthia J.

doi:10.2174/1874364101711010176

Cited by 61 publications

(60 citation statements)

References 91 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Furthermore, Luz A and coworkers summarized previous literatures on corneal biomechanics, and predicted corneal biomechanical assessments would have a bright future for ectasia detection 34 . As Corvis ST came into use, the consistent air puff maximal pressure was measured in every examination and more detailed information of corneal deformation could be evaluated 17 . Recent reviews summarized the practical application of Corvis ST parameters in normal eyes, KC eyes, and KE eyes 15,17 .…”

Section: Discussionmentioning

confidence: 99%

“…As Corvis ST came into use, the consistent air puff maximal pressure was measured in every examination and more detailed information of corneal deformation could be evaluated 17 . Recent reviews summarized the practical application of Corvis ST parameters in normal eyes, KC eyes, and KE eyes 15,17 . However, the studies in terms of the comparisons among LASIK eyes, KE eyes and KC eyes are still limited.…”

Section: Discussionmentioning

confidence: 99%

“…With the updated versions of Corvis ST software, new parameters were added for a better assessment of the biomechanical parameters 17 . Several studies found that the new parameters had the potential ability to distinguish KC eyes from normal eyes 18 .…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of new Corvis ST parameters in normal, Post-LASIK, Post-LASIK keratectasia and keratoconus eyes

Yang

Fan

et al. 2020

Sci Rep

View full text Add to dashboard Cite

The aim of this study was to evaluate the distribution of new Corneal Visualisation Scheimpflug technology (corvis St) parameters in normal, post-laser in situ keratomileusis (LASiK), post-LASiK keratectasia (Ke) and keratoconus (Kc) eyes, and explore the diagnostic ability of these parameters in distinguishing KE from LASIK eyes. Twenty-three normal eyes, 23 LASIK eyes, 23 KE eyes and 23 KC eyes were recruited in this study. the following new corvis St parameters were measured: Max inverse Radius, deformation amplitude (DA) Ratio Max [2 mm], Pachy Slope, DA Ratio Max [1 mm], Ambrosio's relational thickness horizontal (ARTh), Integrated Radius, stiffness parameter at first applanation (SP-A1) and Corvis biomechanical index (CBI). The general linear model, linear regression model, relation analysis and receiver operating characteristic (Roc) curve were performed. the Max inverse Radius, DA Ratio Max [2 mm], Pachy Slope, DA Ratio Max [1 mm], Integrated Radius and CBI in LASIK eyes, KE eyes and KC eyes were higher than in normal eyes, while the ARTh and SP-A1 parameters were lower than in normal eyes. The KE eyes had higher Max Inverse Radius, DA Ratio Max [2 mm], Pachy Slope, DA Ratio Max [1 mm], Integrated Radius, and lower SP-A1 value than LASIK eyes (all P < 0.05). The central corneal thickness was related to the pachy Slope (r = −0.485), ARTh (r = −0.766), SP-A1 (r = 0.618) in Ke eyes (all P < 0.05). The area under the ROC curve of Integrated Radius, Max Inverse Radius, DA Ratio Max [2 mm] and SP-A1 were above 0.800 in identifying KE from LASIK eyes. Thus, the new Corvis ST parameters were different between LASIK and KE eyes, suggesting that they might be helpful in distinguishing Ke eyes from LASiK eyes. However, a further multi-center and large sample study is necessary to confirm these findings.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of new Corvis ST parameters in normal, Post-LASIK, Post-LASIK keratectasia and keratoconus eyes

Yang

Fan

et al. 2020

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Interestingly, mild, early or fruste keratoconus may be challenging to detect, requiring the conscious use of advanced corneal imaging. 3,4 We report the case who presented for second opinion due to severe symptoms related to quality of vision after toric multifocal IOL implantation in whom the diagnosis of mild ectatic disease was done, indicating IOL exchange.…”

Section: Introductionmentioning

confidence: 99%

“…1,2 In addition, detecting mild disease and its progression in young patients has gained its momentum due to the change in paradigm related to surgery for keratoconus and related diseases. 3 Nevertheless, this has increased importance when planning refractive cataract surgery, especially in candidates for receiving premium multifocal lenses. Interestingly, mild, early or fruste keratoconus may be challenging to detect, requiring the conscious use of advanced corneal imaging.…”

Section: Introductionmentioning

confidence: 99%

Importance of Screening for Ectatic Corneal Disease Prior to Multifocal Intraocular Lens

Ambrósio¹,

Hallal²

2018

International Journal of Keratoconus and Ectatic Corneal Diseases

View full text Add to dashboard Cite

Aim: This article reports the case of a patient with severe symptoms related to bad quality of vision after toric multifocal intraocular lens (IOL) that was diagnosed with mild keratoconus. Materials and methods:To present a case report and prospectively review of the literature, considering the relevance of screening ectaticconreal disease prior to refractive cataract (or lens) surgery. Results:The patient was dissatisfied, seeking a second opinion after the implantation of a toric multifocal IOL in the left eye. The IOL was properly centered and surgery had no complications. The preoperative refraction was −4.00 − 1.50 × 160, giving 20/40. Patient denied any history of keratoconus or transplant in his family. After cataract surgery, uncorrected distance vision acuity (UDVA) was 20/60, and J4 for near. Manifest refraction was + 2.00 − 0.50 × 130, giving 20/30. Corneal topography, tomography, and biomechanical assessments indicated the diagnosis of mild keratoconus. The patient was advised for IOL exchange, which was successfully done for a monofocal aspheric IOL. The patient was satisfied with the final result, presenting a final UDVA of 20/25, J3, and manifest refraction of +0.75 − 0.50 × 105, giving 20/20. Conclusion:Screening for corneal abnormalities including ectatic corneal disease is fundamental prior to the indication of a premium lens. Advanced corneal imaging plays a fundamental role to help select candidates for multifocal IOLs, as for individualized planning of refractive cataract surgery.

show abstract