Corneal ectasia after trabeculectomy with mitomycin C application

Lin, Chang‐Ping; Liu, Yi-Tseng; Chen, Chen-Wu

doi:10.1136/bjo.83.5.628b

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…Die bisherigen klinischen Erfahrungen über die unerwünschten Nebenwirkungen von topisch appliziertem Mitomycin wurden im Rahmen der operativen Pterygium-und Glaukombehandlung gewonnen. Die dort gesehenen Nebenwirkungen waren Keratopathien (Hornhautödem, Hornhautperforation, Keratektasien), eine Kalzifikation der Sklera, eine Iritis, eine Cataracta complicata und auch ein Sekundärglaukom [4,11,20]. Obwohl diese unerwünschten Reaktionen in der Regel nur nach einer länger durchgeführten Gabe eingetreten sind, ist eine Hornhautperforation auch nach einer einmaligen Gabe beschrieben worden.…”

Section: Diskussionunclassified

Topisches Mitomycin C zur Rezidivprophylaxe von Haze nach erneuter Excimer-Laser-photorefraktiver Keratektomie (PRK) - Klinische Pilotstudie an 5 Patienten1

Mohrenfels

Hermann²,

Gabler³

et al. 2001

Klin Monatsbl Augenheilkd

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Section: Diskussionunclassified

Topisches Mitomycin C zur Rezidivprophylaxe von Haze nach erneuter Excimer-Laser-photorefraktiver Keratektomie (PRK) - Klinische Pilotstudie an 5 Patienten1

Mohrenfels

Hermann²,

Gabler³

et al. 2001

Klin Monatsbl Augenheilkd

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Trabeculectomy-Related Corneal Complications

Nofal¹,

Sayyad²

2015

Glaucoma

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Dellen-like keratopathy associated with glaucoma drainage devices

Fenzl

Moshirfar

Gess

et al. 2014

WJCC

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To report the first case of dellen-like keratopathy with superior corneal thinning associated with implantation of glaucoma drainage devices. A 70-year-old male with a history of primary open angle glaucoma and dry eye disease underwent placement of glaucoma drainage devices with antimetabolite application in both eyes. Prior to placement, minimal refractive error was noted on manifest refraction. Several years later, the patient was referred for decreased vision and corneal irregularity. Examination showed pathologic corneal curvature, superior corneal thinning, and epithelial demarcation lines immediately anterior to the glaucoma drainage devices in both eyes. The epithelium remained intact with no evidence of limbal stem cell deficiency. Manifest refraction revealed a large change in both eyes. Topography was used to confirm the presence of irregular corneal curvature anterior to the glaucoma drainage devices. Dellen-like keratopathy with superior thinning is a rare sequela after implantation of a glaucoma drainage device that must be considered in elderly patients who undergo glaucoma surgery. It is likely related to a combination of tear film alteration related to previously large anterior blebs, antimetabolite application, and aqueous humor flow patterns around the drainage devices. Treatment should focus on lubrication.

show abstract

Corneal ectasia after trabeculectomy with mitomycin C application

Cited by 3 publications

References 4 publications

Topisches Mitomycin C zur Rezidivprophylaxe von Haze nach erneuter Excimer-Laser-photorefraktiver Keratektomie (PRK) - Klinische Pilotstudie an 5 Patienten1

Topisches Mitomycin C zur Rezidivprophylaxe von Haze nach erneuter Excimer-Laser-photorefraktiver Keratektomie (PRK) - Klinische Pilotstudie an 5 Patienten1

Trabeculectomy-Related Corneal Complications

Dellen-like keratopathy associated with glaucoma drainage devices

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