Corneal Lenticule Implantation in Keratoconus Disease with Relex Smile Surgery

Semiz, Faruk; Lokaj, Anita Syla; Hima, Njomëza; Semiz, Olcay

doi:10.31080/asop.2020.03.0140

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The Carl ZEISS VisuMax femtosecond laser (frequency 500 kHz) was used to treat residual myopic refractive error with the SMILE technique 4 months after cataract surgery [ 5 – 9 ]. First, topical anesthetic drops were applied to the cornea.…”

Section: Methodsmentioning

confidence: 99%

SMILE for the Treatment of Residual Refractive Error After Cataract Surgery

Semiz¹,

Lokaj²,

Musa³

et al. 2022

Ophthalmol Ther

Self Cite

View full text Add to dashboard Cite

Introduction In the context of managing patients’ expectations and satisfaction regarding visual acuity after cataract surgery, we aimed to investigate the improvement in visual acuity and patient satisfaction after small-incision lenticule extraction (SMILE) in pseudophakic (trifocal intraocular lens, IOL) patients with residual myopic refraction after cataract surgery. Methods Seventy-six patients (82 eyes) who underwent cataract surgery with ZEISS AT LISA tri 839MP IOL implantation were included in this retrospective study. The included patients were 56–79 years old, wanted spectacle independence, and had preoperative myopic refraction between − 1.0 and − 2.25 diopters (D) and astigmatism between − 0.75 and − 1.75 D. The treatment status of these patients was defined as trifocal IOL ( n = 82). SMILE was performed in patients who were dissatisfied after cataract surgery, and these patients were followed up for 1 year on average. We evaluated visual acuity and satisfaction and further examined laser vision correction and satisfaction levels in patients who were dissatisfied after trifocal IOL implantation. Results The possible reasons for patient dissatisfaction were reading books, using a computer, and driving at night. After SMILE, the residual myopic refractive error (spherical) decreased significantly from − 2.08 ± 0.28 [− 2.25 to − 1.0] preoperatively to − 0.25 ± 0.20 − 0.5 to 0] 1 year postoperatively ( p < 0.001). Additionally, the uncorrected distance visual acuity increased from 0.65 ± 0.08 [0.52–0.7] logMAR preoperatively to 0.09 ± 0.02 [0.05–0.1] logMAR at 1 month postoperatively ( p < 0.001), 0.09 ± 0.02 [0.05–0.1] logMAR at 6 months postoperatively, and 0.06 ± 0.02 [0.05–0.1] logMAR at 12 months postoperatively ( p < 0.001). Patient satisfaction measures after SMILE (reading, night driving, and using a computer) were significantly improved. Conclusion SMILE is a reliable method for treating residual refraction after cataract surgery, as it provides results in the shortest time without complications and increases patient satisfaction. Trial Registration The protocol was registered on clinicaltrials.gov (NCT04693663).

show abstract

Section: Methodsmentioning

confidence: 99%

SMILE for the Treatment of Residual Refractive Error After Cataract Surgery

Semiz¹,

Lokaj²,

Musa³

et al. 2022

Ophthalmol Ther

Self Cite

View full text Add to dashboard Cite

show abstract

Fresh Human Myopic Lenticule Intrastromal Implantation for Keratoconus Using SMILE Surgery in a Long-term Follow-up Study: Ultrastructural Analysis by Transmission Electron Microscopy

Semiz¹,

Lokaj²,

Tanrıverdi³

et al. 2022

J Refract Surg

View full text Add to dashboard Cite

PURPOSE: To investigate new intrastromal histological structures that develop after myopic human lenticular implantation in keratoconus with femtosecond laser–assisted small incision lenticule extraction (SMILE) surgery using transmission electron microscopy. METHODS: Sixty eyes with advanced keratoconus indicated for corneal transplantation were included in this study. Fresh myopic lenticular implants were placed in all eyes through SMILE surgery. Lenticular implants were extracted from patients with myopic refractive errors of the cornea, untreated keratoconus, and treated keratoconus following 1, 2, and 3 years of surgery. These five lenticular samples were examined under the electron microscope and compared. RESULTS: Disorganized and thinned collagen fibers were observed in the stroma with degenerative stromal cells (telocyte-like cells and keratocytes) in the keratoconic cornea. Apoptotic bodies and cell debris were easily observed near the disorganized fibers. In contrast, the myopic refractive error of the control and treatment groups demonstrated well-organized parallel lamellar structures. Healthy keratocytes and telocyte-like cells were observed in samples obtained 1, 2, and 3 years after lenticular implantation. Thus, telocyte-like cells may be activated by appropriate stimuli, such as stem cells, and be involved in stromal regeneration. CONCLUSIONS: Fresh myopic intrastromal lenticular implantation is a safe, economical, and reliable technique that leads to increased corneal thickness, improved visual acuity, and the regeneration of healthy keratocytes and telocyte-like cells that are involved in stromal regeneration. [ J Refract Surg . 2022;38(8):520–528.]

show abstract

Corneal Lenticule Implantation in Keratoconus Disease with Relex Smile Surgery

Cited by 2 publications

References 0 publications

SMILE for the Treatment of Residual Refractive Error After Cataract Surgery

SMILE for the Treatment of Residual Refractive Error After Cataract Surgery

Fresh Human Myopic Lenticule Intrastromal Implantation for Keratoconus Using SMILE Surgery in a Long-term Follow-up Study: Ultrastructural Analysis by Transmission Electron Microscopy

Contact Info

Product

Resources

About