Light and Specular Microscopy of the Cornea 2017
DOI: 10.1007/978-3-319-48845-5_3
|View full text |Cite
|
Sign up to set email alerts
|

Corneal Storage, Hypothermia, and Organ Culture

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
5

Citation Types

0
8
0

Year Published

2021
2021
2024
2024

Publication Types

Select...
6

Relationship

2
4

Authors

Journals

citations
Cited by 6 publications
(8 citation statements)
references
References 72 publications
0
8
0
Order By: Relevance
“…Globally, two protocols are employed in the storage of donor corneas: organ culture at 28–37 °C and hypothermic storage at 2–8 °C [ 9 ]. While organ culture is used almost exclusively in Western Europe, in the USA 98% of retrieved corneas are stored in hypothermic solution [ 10 , 11 ]. Whereas hypothermic storage is technically simpler and has a lower cost per unit, corneoscleral rims may be stored for 4–5 weeks in organ culture compared with up to only 14 days in hypothermic storage [ 10 12 ].…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Globally, two protocols are employed in the storage of donor corneas: organ culture at 28–37 °C and hypothermic storage at 2–8 °C [ 9 ]. While organ culture is used almost exclusively in Western Europe, in the USA 98% of retrieved corneas are stored in hypothermic solution [ 10 , 11 ]. Whereas hypothermic storage is technically simpler and has a lower cost per unit, corneoscleral rims may be stored for 4–5 weeks in organ culture compared with up to only 14 days in hypothermic storage [ 10 12 ].…”
Section: Introductionmentioning
confidence: 99%
“…Theoretically, cell processes can continue in organ culture, and there is evidence of endothelial migration towards wounds in organ culture conditions [ 13 ]. There is, however, no conclusive evidence showing superior graft survival with organ culture or hypothermic storage [ 11 , 14 , 15 ]. Some retrospective studies suggest superior graft survival with organ culture, while others report no difference [ 15 ].…”
Section: Introductionmentioning
confidence: 99%
“…Although perioperative culturing of the corneal rim is aimed to minimize the risk of postoperative infections, there are no specific perioperative protocols and standards in the medical literature for culturing the corneal rim, and some reports claimed that such testing has no value in predicting infectious complications post-keratoplasty [ 1 , 2 ]. Nowadays, there are two basic approaches to preserve corneas for grafting: hypothermic and organ culture methods [ 3 ].…”
Section: Introductionmentioning
confidence: 99%
“…On the day of surgery, the cornea is trephined in the operating room, and the corneal rim is then sent for a microbiology workup. The main advantages of hypothermic storage are faster, immediate availability of tissue and reduced cost compared to the organ culture method [ 3 ].…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation