Coronary Angiographic Findings Among the Left Bundle Branch Block Patients

Iqbal, Abu Tarek; Ayub,; Salehuddin,; Ahmed, Khurshed

doi:10.3329/uhj.v12i2.36389

Cited by 2 publications

(1 citation statement)

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“…A study evaluating the angiographic characteristics of symptomatic patients with major LBBB concluded that this is rather correlated with normal epicardial arteries; more precisely, 64% of patients had angiographic results without changes [ 21 , 22 , 23 ], which was also demonstrated in our research. However, this study, as well as most of the literature studies addressing this subject, does not describe the differences between the two sexes from the point of view of the grade or type of coronary involvement.…”

Section: Discussionsupporting

confidence: 80%

Major Left Bundle Branch Block and Coronary Heart Disease—Are There Any Differences between the Sexes?

Gurzau

Dădârlat-Pop

Caloian

et al. 2021

JCM

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Left bundle branch block is not a benign pathology, and its presence requires the identification of a pathological substrate, such as ischemic heart disease. Left bundle branch block appears to be more commonly associated with normal coronary arteries, especially in women. The objectives of our study were to describe the particularities of left bundle branch block in women compared to men with ischemic heart disease. Result: We included seventy patients with left bundle branch block and ischemic heart disease, with a mean age of 67.01 ± 8.89 years. There were no differences in the profile of risk factors, except for smoking and uric acid. The ventricular depolarization (QRS) duration was longer in men than women (136.86 ± 8.32 vs. 132.57 ± 9.19 msec; p = 0.018) and also men were observed to have larger left ventricular diameters. Left bundle branch block duration was directly associated with ventricular diameters and indirectly associated with left ventricular ejection fraction value, especially in women (R = −0.52, p = 0.0012 vs. R = −0.50, p = 0.002). In angiography, 80% of women had normal epicardial arteries compared with 65.7% of men; all these patients presented with microvascular dysfunction. Conclusion: The differences between the sexes were not so obvious in terms of the presence of risk factors; instead, there were differences in electrocardiographic, echocardiographic, and angiographic aspects. Left bundle branch block appears to be a marker of microvascular angina and systolic dysfunction, especially in women.

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Section: Discussionsupporting

confidence: 80%