Coronary artery calcification scoring system based on the coronary artery calcium data and reporting system (CAC-DRS) predicts major adverse cardiovascular events or all-cause death in patients with potentially curable lung cancer without a history of cardiovascular disease

Aortic arch calcification with pericardial fat mass detected on a single chest X-ray image is closely associated with the predictive variables of future cardiovascular disease

“…The results of our study concluded that AAC on chest X-ray examination may be a surrogate marker for future CVD risk assessment. Arterial calcification has previously been shown to be related to traditional CVD risk factors and mortality [3][4][5][6]28]. The presence of AAC indicates the significant associations of aortic calcification [6,29] and mortality [7,30].…”

“…To establish new tools for evaluating CVD risk, we have examined the aortic arch calcification (AAC) and pericardial fat (PF) mass detected with chest X-ray examinations. Arterial calcification is a useful variable for evaluating atherosclerosis and mortality [3,4]. Calcified lesions of the aortic arch have been found by several studies to be significantly associated with risk factors of CVD [5,6].…”

Prediction models for treatment-induced cardiac toxicity in patients with non-small-cell lung cancer: A systematic review and meta-analysis

“…Of the 28 included papers, seven studies developed prediction models for late cardiac toxicity after (chemo-)radiotherapy [15][16][17][18][19][20][21]. We identified 20 prediction models for acute cardiac events after surgery [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] and one study estimated the risk of developing cardiovascular events after immunotherapy (nivolumab and pembrolizumab) [42].…”

“…Twelve studies (42.9%) included patients who underwent surgical resection as the sole treatment method [22,[26][27][28][29][30]33,[35][36][37]39,40] and eight studies (28.6%) assessed cardiac events after combined therapy of surgery with chemotherapy and/or radiotherapy [23][24][25]31,32,34,38,41]. Five studies (17.9%) considered radiotherapy (3D-conformal radiotherapy, intensity-modulated radiotherapy, or radioactive implant) with or without chemotherapy as the eligibility criteria of their study samples [15,[17][18][19][20].…”

“…Implicit or explicit predictor importance assessment was performed in five studies mostly focusing on cardiac parameters (e.g. coronary artery calcium score, whole heart volume, or dose-volume metrics from the substructures of the heart) [16,18,21,27,41].…”