Coronary Heart-Attacks in East London

Pedoe, Hugh Tunstall; Clayton, David; Morris, J.N.; Brigden, Wallace; McDonald, Lawson

doi:10.1016/s0140-6736(75)90233-0

Cited by 165 publications

(18 citation statements)

References 4 publications

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“…Rates among women were uniformly lower. Despite these smoking habits, the study confirms normal population data indicating that the presence of apparently ischemic chest pain or documented myocardial infarction was lower among WIB than among matched White diabetic patients (6,7). Rates in the older diabetic Jamaicans were also low.…”

Section: Multiple Logistic Regression For Complicationssupporting

confidence: 82%

Black West Indian and Matched White Diabetics in Britain Compared With Diabetics in Jamaica: Body Mass, Blood Pressure, and Vascular Disease

Cruickshank

Alleyne

1987

Diabetes Care

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This study was designed to compare the prevalence of obesity, high blood pressure, diabetic vascular disease, and risk factors in Black West Indians who had emigrated to Britain (WIB) with those in Whites in England and among diabetic Jamaicans in Jamaica. Seventy-seven consecutive WIB patients were matched for age, sex, known duration of diabetes, and type of treatment of diabetes with 74 Whites from the same diabetes clinic in England. In Jamaica, a systematic random sample (95 women, 36 men) was studied. There was no difference in age at diagnosis between WIBs and Jamaicans. Effort chest pain (possible angina) was less frequent in WIBs (9%) or Jamaicans (3%) than in Whites (25%). Cigarette smoking was more common in WIBs than in Whites but still low in Jamaicans. Body mass index was greatest in WIB women (85%), significantly more than in matched White (52%) or Jamaican women (45%); 40% of White men and WIB men were obese, significantly more than Jamaicans (15% obese). Systolic blood pressure was similar, but diastolic blood pressure was significantly greater in WIBs than in matched White subjects. The prevalence of casual hypertension was high (greater than 40%) in all groups, often despite treatment. Cataracts were significantly more frequent in WIB and Jamaican groups than in Whites. Total background retinopathy after correcting for duration of diabetes did not differ between groups, and there were no significant differences in other complication rates. Levels of HbA1 were lower in Whites than in the other groups. Regression analysis showed that systolic blood pressure was most consistently related to complications, particularly retinopathy, independent of ethnic group and duration.(ABSTRACT TRUNCATED AT 250 WORDS)

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Section: Multiple Logistic Regression For Complicationssupporting

confidence: 82%

Black West Indian and Matched White Diabetics in Britain Compared With Diabetics in Jamaica: Body Mass, Blood Pressure, and Vascular Disease

Cruickshank

Alleyne

1987

Diabetes Care

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“…In the Tower Hamlets study in East London half of those suffering heart attacks had a previous history of ischaemic heart disease, and an appreciable minority were already unfit for work, mainly because of recognised cardiovascular disease. 8 The WHO International Collaborative Study with heart attack registers in 19 European centres, as well as Australia (Perth) and Israel (Tel-Aviv), covered a population of 3-6 million men and women aged 20-64 years.32 In this study, two thirds of the men and four fifths of the women were already suffering from some form of cardiovascular disease by the time they experienced acute myocardial infarction or sudden death. The commonest preceding histories were hypertension, angina, and myocardial infarction.…”

Section: Comparison With Other Studiesmentioning

confidence: 96%

Prevalence of ischaemic heart disease in middle aged British men.

Shaper¹,

Cook²,

Walker³

et al. 1984

Heart

109

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SUMMARY The prevalence of ischaemic heart disease was determined by an administered questionnaire and electrocardiography in 7735 men aged 40-59 years drawn at random from general practices in 24 British towns. Overall, one quarter of these men had some evidence of ischaemic heart disease on questionnaire or electrocardiogram or both. On questionnaire, 14% of men had possible myocardial infarction or angina, with considerable overlap of the two syndromes. The prevalence of possible myocardial infarction combined with angina and of definite angina only showed a fourfold increase over the age range studied.Electrocardiographic evidence of ischaemic heart disease (definite or possible) was present in 15% of men, there being myocardial infarction in 4.2% and myocardial ischaemia in 10-3%. Electrocardiographic evidence of myocardial infarction increased fourfold over the age range studied. There was considerable overlap of questionnaire and electrocardiographic evidence of ischaemic heart disease. Nevertheless, more than half of those with possible myocardial infarction combined with angina had no resting electrocardiographic evidence of ischaemic heart disease, and half of those with definite myocardial infarction on electrocardiogram had no history of chest pain at any time. This national population based study strongly suggests that the prevalence of ischaemic heart disease in middle aged British men is greater than has been indicated by previous studies based on occupational groups.Ischaemic heart disease is a major cause of incapacity and death in middle aged and elderly men and women in Great Britain. There are reasonably sound data on deaths due to ischaemic heart disease' but less information regarding its prevalence-that is, the proportion of people in the community with symptoms or signs of ischaemic heart disease or both. Several major prevalence studies of ischaemic heart disease have been carried out, usually based on one geographic area2 and often restricted to one occupational group.3 It is difficult to generalise from such studies to the British population at large, as there are considerable geographic and socioeconomic variations in cardiovascular disease mortality.46 Information from heart attack registers suggests that these variations affect non-fatal as well as fatal ischaemic heart disease events, and thus the prevalence of the disease is likely to show as much geographic variation as its mortality.78 The British Regional Heart Study is concerned with such geographic variations in cardiovascular disease and includes a survey of middle aged men in 24 British towns.9 10 The present report, based on the findings of this study, describes the overall prevalence of ischaemic heart disease as determined by an administered questionnaire and electrocardiography. A companion report (p 606) analyses the ability of subjects in this study to recall a diagnosis of ischaemic heart disease made by a doctor. " Further reports will deal with the effects of social class and town of residence on the prevalence of i...

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“…Epidemiologic studies have shown that South Asians who have migrated to Western countries have a higher prevalence of CHD than do Caucasians of European ancestry [5][6][7][8]. South Asians not only have a higher prevalence of CHD but have higher mortality than those of European and Chinese ethnicity [9].…”

Section: Chd In Migrant South Asiansmentioning

confidence: 99%