Corporoplasty Using Buccal Mucosa Graft in Peyronie Disease: Is It a First Choice?

Buccal mucosa is a promising graft in Peyronie’s disease surgery. Our experience and a brief literature review on autologous grafting materials

“…Modifying the procedure from a plaque excision with substitution to an incision with insertion of a buccal mucosa patch, Cormio and co-workers (12) reported in 15 patients, operated without complications (56.3 years of mean age and 72° of mean penile curvature degree), a 100% of penile straightening, 1.8-cm mean increase in length of affected side, no curvature recurrence or de novo erectile dysfunction, 1.6 mean increase in IIEF-5 score, and patient and partner satisfaction of 93.3% and 100%, respectively. These results were recently confirmed by Zucchi et al (13) in 32 patients treated with this procedure between 2006 and 2013. In their evaluable 28 cases, they reported no complications and a curvature relapse, after 1 year, in 3.5%.…”

“…Globally, in terms of overall success rate, BMG series reported results between 87.5% and 100% (Table 3). Patient satisfaction rate ranged from 85-100% when investigated (12)(13) and no decrease is observed over the years. The rate of "de novo" erectile dysfunction ranged between 0% to 18%.…”

“…Moreover, many studies did not include complete information about the outcome of surgery such as satisfaction rate or globally post operative ED. When published, the outcomes are comparable, especially between pericardial graft (10-11) and buccal mucosa graft series (12)(13). In the present paper we explain how the characteristics of an ideal graft were achieved with this surgical procedure and outcomes data obtained from our series of 17 patients who underwent a complex corporoplasty using a buccal mucosa graft, compared with literature results.…”

“…No patch bulging are yet reported. Only a case of "seroma" was cited but not reported (13). Loss of glans sensitivity or recurrent erection penile pain were common symptoms reported by the patients, especially in the first three or six months from the intervention.…”

“…These symptoms are safely managed with the common analgesic/anti-inflammatory drugs. At the least, the need of a multiple harvesting from cheek is very rare and the elasticity of buccal mucosa permits to avoid any patch oversizing respect to plaque dimensions (13). Prior of these evidences, the venous graft was advocated as the more physiologic than others autologous tissue (30)(31).…”