Correction: Limited Clinical Utility of Remote Ischemic Conditioning in Renal Transplantation: A Meta-Analysis of Randomized Controlled Trials

Zhou, Changcheng; Ge, Yu‐Zheng; Yao, Wen-Tao; Wu, Ruizhi; Hui, Xidong; Lu, Tian-Ze; Li, Minghao; Song, Kaiwei; Wang, Min; Zhu, Yunpeng; Zhu, Meng; Geng, Liguo; Gao, Xiaofei; Zhou, Lin; Zhang, Shengli; Zhu, Jun; Jia, Ru

doi:10.1371/journal.pone.0204184

PLoS ONE

2018

DOI: 10.1371/journal.pone.0204184

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Correction: Limited Clinical Utility of Remote Ischemic Conditioning in Renal Transplantation: A Meta-Analysis of Randomized Controlled Trials

Changcheng Zhou¹,

Yu‐Zheng Ge²,

Wen-Tao Yao³

et al.

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The method of distant preconditioning and results of its application in renal transplantation from the living family donor

Kyrychenko

Biliaiev

Davydenko³

et al. 2021

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Objective. Elaboration of method for the intraoperative ischemic-reperfusion trauma softening - distant ischemic preconditioning and investigation of results of its introduction into clinical practice. Materials and methods. The method of distant ischemic preconditioning elaborated have included four procedures the air inflation into the flap for the arterial pressure measuring by 40 mm Hg over the level of systolic arterial pressure, 5 min of duration in every one, with consequent 5-minute intervals for the air release from the flap. The procedure of a distant ischemic preconditioning was conducted after introduction into narcosis, but before the donor's nephrectomy in 30 patients (the main group). The procedure was not conducted in 30 such patients. Results. The procedure elaborated permits to enhance the glomerular filtration significantly in 6 and 12 mo, to reduce the rate of partial delay of the transplant functioning, its acute rejection and primary dysfunction. Conclusion. The procedure of a distant ischemic preconditioning elaborated improves the transplanted kidney function.

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The method of distant preconditioning and results of its application in renal transplantation from the living family donor

Kyrychenko

Biliaiev

Davydenko³

et al. 2021

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Remote Donor Preconditioning for Increasing Transplant Survival in the Recipient’s Body During the Kidney Transplantation From the Living-Related Donor

2022

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The aim: To estimate the protective effect of remote ischemic preconditioning (RIPC) on kidney transplants harvested from living related donors. Materials and methods: To achieve the claimed aim, there were examined 60 donor-recipient couples, where kidney transplant donors were living-related. All donors had the same anaesthetic management. The first group (n = 30) received RIPC which included four procedures of cuff inflations each lasting 5 minutes followed by 5-minute intervals of cuff deflation to measure blood pressure up to 40 mm Hg above systolic blood pressure on the shoulder. Patients of the second group (controls) did not experience RIPC (n = 30) and control group without RIPC. Results: RIPC resulted in a statistically significant (P<0.05) increase in GFR of the transplanted kidney from 66±5 mL /min to 63±4 mL /min after 3 months, from 69±3 mL /min to 61±5 mL /min after 6 months, from 63±2.5 mL /min to 57±3 mL /min after 12 months; a 3-fold reduced partial delay of graft function; a 2-fold decreased incidence of acute kidney transplant rejection times; 1.5-fold decline in the incidence of primary non-function; and 1.4-fold tCr50 acceleration (p = 0.16). The follow-up period lasted for a year after transplantation. Conclusions: RIPC during organ harvesting improved graft ischemic protection and increased functioning efficiency in the recipient.

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Correction: Limited Clinical Utility of Remote Ischemic Conditioning in Renal Transplantation: A Meta-Analysis of Randomized Controlled Trials

Cited by 2 publications

References 4 publications

The method of distant preconditioning and results of its application in renal transplantation from the living family donor

The method of distant preconditioning and results of its application in renal transplantation from the living family donor

Remote Donor Preconditioning for Increasing Transplant Survival in the Recipient’s Body During the Kidney Transplantation From the Living-Related Donor

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