Patient satisfaction with the shape and appearance of their nose after orthognathic surgery-based skeletofacial reconstruction is an important, but often overlooked, outcome. We assessed the nose-related outcomes through a recently developed patient-reported outcome instrument and a widely adopted 3D computer-based objective outcome instrument, to verify any correlation in the results produced by these tools. We collected FACE-Q nose appearance reports (2 scales) and 3D nasal morphometry (10 parameters) from patients with class III skeletal pattern and congenital cleft lip palate deformity (n = 23) or developmental dentofacial deformity (n = 23) after (>12 months) skeletofacial reconstruction. The cleft and dentofacial cohorts demonstrated significantly (p < 0.001) poorer satisfaction scores with regard to the FACE-Q nostrils scale than the normal age-, gender-, and ethnicity-matched subjects (n = 107), without any significant difference in FACE-Q nose scale. The cleft cohort had significantly (p < 0.001) smaller nasal length, nasal tip projection, and columellar angle and greater nasal protrusion, alar width, and columellar-labial angle values than the dentofacial and normal cohorts; however, there were no significant differences between the dentofacial versus normal cohorts. The FACE-Q nose and nostrils scales were significantly (p < 0.001; r = −0.26-0.27) correlated to the results of the 3D morphometric analysis, with regard to nasal length, alar width, columella angle, and columellar-labial angle parameters. This study revealed differences in satisfaction with the appearance of the nose according to the type of underlying deformity, and demonstrated a significant correlation (low correlation coefficients) between the patient-reports and 3D image-based outcome measure tools, which has implications for multidisciplinary-centered research, auditing, and clinical care. Facial deformities associated with abnormal maxillo-mandibular relationships, such as congenital cleft lip and palate and developmental dentofacial deformities, significantly affect oral function and facial aesthetics 1,2. Skeletofacial reconstruction using orthognathic surgery principle is a successful treatment modality for these abnormalities 3-5. However, a number of post-surgical facial modifications are the primary causes of concern among the patients, particularly changes in the nasal morphology 6. A growing number of studies have addressed this issue by adopting three-dimensional (3D) nasal measurements 6-15 , but the effects of skeletofacial reconstruction are beyond these imaging-guided outcome metrics 1,4,5. The patient satisfaction with the appearance of their nose is an important, albeit often overlooked, outcome parameter after orthognathic surgery. Therefore, including a patient's self-perception by employing patient-reported outcome (PRO) techniques may help clinicians to understand the health-related concerns of the patient 16,17. Literature reviews 4,5 have revealed that a plethora of PRO instruments have been utilized to primaril...