Correction to: Oral vaccination of dogs: a well-studied and undervalued tool for achieving human and dog rabies elimination

Cliquet, Florence; Guiot, Anne-Laure; Aubert, Michel; Robardet, Emmanuelle; Rupprecht, Charles E.; Meslin, F. X.

doi:10.1186/s13567-018-0579-x

Cited by 6 publications

(2 citation statements)

References 1 publication

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“…Decades of debate over the potential role of ORV for dogs has left a confusing landscape of guidance and perspectives (49)(50)(51)(52)(53). Here, we discuss the greatest deterrents to the inclusion of ORV in routine dog vaccination programs and how to encourage their safe and cost-effective use.…”

Section: Factors Contributing To Underutilization Of Oral Rabies Vaccmentioning

confidence: 99%

Role of Oral Rabies Vaccines in the Elimination of Dog-Mediated Human Rabies Deaths

Wallace¹,

Cliquet²,

Fehlner-Gardiner³

et al. 2020

Emerg. Infect. Dis.

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S ince the advent of Pasteur's germ theory and the general acceptance that infectious diseases do not develop spontaneously, humankind has strived to reduce and eliminate pathogens that pose a serious public health threat. Incorporating routine vaccinations to control human diseases such as pneumonia, diarrhea, pertussis, measles, and polio contributed to the prevention of >10 million human deaths during 2010-2015 (1). Intensive global efforts toward disease eradication have focused on only a few diseases, including Guinea worm disease (dracunculiasis) (>99% reduction in human cases), smallpox (eradicated in 1980), rinderpest (eradicated in 2011), polio (99% reduction in human cases), and lymphatic filariasis (73% reduction in human cases) (2-6). Those disease eradication efforts have focused on pathogens that are host-restricted or affect only a single host. In 2015, the world called for action by setting a goal of zero human dog-mediated rabies deaths by 2030 worldwide. In 2018, the World Health Organization (WHO), the World Organisation for Animal Health (OIE), the Food and Agriculture Organization of the United Nations, and the Global Alliance for Rabies Control launched the Global Strategic Plan for global elimination of dog-mediated human rabies deaths by 2030, which represents the first major effort to eliminate a classical zoonosis and poses

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Section: Factors Contributing To Underutilization Of Oral Rabies Vaccmentioning

confidence: 99%

Role of Oral Rabies Vaccines in the Elimination of Dog-Mediated Human Rabies Deaths

Wallace¹,

Cliquet²,

Fehlner-Gardiner³

et al. 2020

Emerg. Infect. Dis.

Self Cite

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“…and evaluation of campaigns. Moreover, delivery methods need tailoring to local contexts, which may require door-to-door vaccinations 44 , capture-vaccinate-release 30 , and possibly supplementary oral vaccination in well-designated areas 45,46 , in addition to central point methods 28 . There is a learning curve to the scaling up of mass dog vaccination.…”

Section: Technical Feasibilitymentioning

confidence: 99%

Zero human deaths from dog-mediated rabies by 2030: perspectives from quantitative and mathematical modelling

2020

Gates Open Res

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Dog-mediated rabies continues to kill tens of thousands of people every year in low- and middle-income countries despite being an entirely vaccine-preventable disease. WHO and partners have launched a global campaign to reach zero human deaths from dog-mediated rabies by 2030. The primary tools for reaching this target are mass dog vaccination to interrupt transmission in domestic dog populations that maintain infection, appropriate post-exposure prophylaxis (PEP) for rabies-exposed persons to prevent the fatal onset of disease, together with education to support their effective uptake. Models have been developed to assess the feasibility, impact and cost-effectiveness of these measures. From these models, we argue that the 2030 target of zero human rabies deaths is achievable, but will require concerted effort, engagement and investment. A proposed Gavi investment in human rabies vaccines has potential to drive progress towards the 2030 target; however, concomitant investment is needed to scale up mass dog vaccination or this target will be missed. Predicted economic benefits of mass dog vaccination vary according to national PEP provisioning and healthcare access. Integrated Bite Case Management can enhance surveillance and rationalize PEP use, but needs adapting to and integrating within local health systems and international reporting systems to improve PEP accountability, monitor impacts and support verification of disease freedom. Modelling approaches need refining to project realistic and geographically specific timelines for achieving targets. Model iterations informed by data on the implementation of interventions can be used to evaluate progress and guide future strategies. Critically such models are needed to advocate for investment, since the greatest risk to the ‘Zero by 30’ strategy is the limited long-term cross-sectoral or targeted financing to support countries to deliver and sustain mass dog vaccination.

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Oral bait handout as a method to access roaming dogs for rabies vaccination in Goa, India: A proof of principle study

Gibson

Yale²,

Vos

et al. 2019

Vaccine: X

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Rabies has profound public health, social and economic impacts on developing countries, with an estimated 59,000 annual human rabies deaths globally. Mass dog vaccination is effective at eliminating the disease but remains challenging to achieve in India due to the high proportion of roaming dogs that cannot be readily handled for parenteral vaccination. Two methods for the vaccination of dogs that could not be handled for injection were compared in Goa, India; the oral bait handout (OBH) method, where teams of two travelled by scooter offering dogs an empty oral bait construct, and the catch-vaccinate-release (CVR) method, where teams of seven travel by supply vehicle and use nets to catch dogs for parenteral vaccination. Both groups parenterally vaccinated any dogs that could be held for vaccination. The OBH method was more efficient on human resources, accessing 35 dogs per person per day, compared to 9 dogs per person per day through CVR. OBH accessed 80% of sighted dogs, compared to 63% by CVR teams, with OBH accessing a significantly higher proportion of inaccessible dogs in all land types. All staff reported that they believed OBH would be more successful in accessing dogs for vaccination. Fixed operational team cost of CVR was four times higher than OBH, at 127 USD per day, compared to 34 USD per day. Mean per dog vaccination cost of CVR was 2.53 USD, whilst OBH was 2.29 USD. Extrapolation to a two week India national campaign estimated that 1.1 million staff would be required using CVR, but 293,000 staff would be needed for OBH. OBH was operationally feasible, economical and effective at accessing the free roaming dog population. This study provides evidence for the continued expansion of research into the use of OBH as a supplementary activity to parenteral mass dog vaccination activities in India.

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Correction to: Oral vaccination of dogs: a well-studied and undervalued tool for achieving human and dog rabies elimination

Cited by 6 publications

References 1 publication

Role of Oral Rabies Vaccines in the Elimination of Dog-Mediated Human Rabies Deaths

Role of Oral Rabies Vaccines in the Elimination of Dog-Mediated Human Rabies Deaths

Zero human deaths from dog-mediated rabies by 2030: perspectives from quantitative and mathematical modelling

Oral bait handout as a method to access roaming dogs for rabies vaccination in Goa, India: A proof of principle study

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