Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice

Abstract

The original version of this article unfortunately contained an error. Andriy Yabluchanskiy's name was incorrectly spelled as Andriy Yabluchanksiy in the original version. The correct spelling is now reflected in this article.

Age‐related alterations in the cerebrovasculature affect neurovascular coupling and BOLD fMRI responses: Insights from animal models of aging

“…Endothelium‐derived nitric oxide (NO) is a potent vasodilatory gasotransmitter and its production and bioavailability has been found to be an important contributor to NVC responses (Toth et al., 2015). In aging, highly reactive excess superoxide (O 2 .− ) molecules sequester free NO to form peroxynitrate (ONOO ‐ ) thus decreasing bioavailability of endothelium‐derived NO, impairing the dilatory capability of the cerebromicrovasculature (Csiszar et al., 2002; Park et al., 2007; Tarantini et al., 2016; Tarantini et al., 2017; Tarantini et al., 2018). In support of the role of endothelial dysfunction in impaired NVC responses, experimental evidence suggests that treatments that restore endothelial function (Tarantini et al., 2018; Tarantini et al., 2019), improve NO bioavailability (Wiedenhoeft et al., 2019), inhibit NADPH oxidases (Park et al., 2007), or reduce cerebrovascular oxidative stress (Kiss et al., 2019; Tarantini et al., 2019; Toth et al., 2014) can improve NVC responses in aged animals.…”