Correlation and Prediction of Metal Toxicity to Aquatic Biota

Kaiser, Klaus L.E.

doi:10.1139/f80-027

Cited by 84 publications

(74 citation statements)

References 3 publications

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“…The difference was possibly attributed to the high concentrations of hexavalent chromium and nickel, both of which are very toxic only to D. magna. The EC50 values for hexavalent chromium to D. magna reported in the literature ranged from 0.10 to 0.36 mg/L, whereas the LC50 of the same metal to fathead minnows ranged between 12.5 and 53.0 mg/L [22][23][24][25][26]. The EC50 values for nickel to D. magna were reported to be from 0.51 to 7.59 mg/L, and for fathead minnows, the reported values ranged from 27 to 32 mg/L [20,27,28].…”

Section: Resultsmentioning

confidence: 96%

Application of a Fish Dna Damage Assay as a Biological Toxicity Screening Tool for Metal Plating Wastewater

Choi¹,

Zong²,

Meier³

2000

Environ Toxicol Chem

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Abstract-The utility of a fish DNA damage assay as a rapid monitoring tool was investigated. Metal plating wastewater was chosen as a sample because it contains various genotoxic metal species. Fish DNA damage assay results were compared to data generated from the conventional whole effluent toxicity (WET) test procedure. The Microtox assay (Azur Environmental, Carlsbad, CA, USA) using Vibrio fischeri was also employed. Eleven samples from two metal plating companies were collected for this evaluation. For the fish DNA damage assay, 7-d-old fathead minnow larvae, Pimephales promelas, were utilized. They were exposed to a series of dilutions at 20ЊC for 2 h. Whole effluent toxicity tests conducted in this study included two acute toxicity tests with Daphnia magna and fathead minnows and two chronic toxicity tests with Ceriodaphnia dubia and fathead minnows. The fish DNA damage assay showed good correlations with both the acute and chronic WET test results, especially with those obtained with fathead minnows. The kappa values, an index of agreement, between the fish DNA damage assay and WET tests were shown to be acceptable (kappa Ն 0.55). These findings imply that this novel fish DNA damage assay has use as an expedient toxicity screening procedure since it produces comparable results to those of the acute and chronic fathead minnow toxicity tests.

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Section: Resultsmentioning

confidence: 96%

Application of a Fish Dna Damage Assay as a Biological Toxicity Screening Tool for Metal Plating Wastewater

Choi¹,

Zong²,

Meier³

2000

Environ Toxicol Chem

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“…A number of the correlations and analyses were run for the entire data set and then re-run with the omission of the lake sites close to Sudbury. 4-7. Copper is moderately toxic (13).…”

Section: Methods and Data Analysismentioning

confidence: 99%

“…Zinc is likely to be released from internal sources by desorption from soils and sediments in response to acidification; it is also deposited as a result of long-range transport (1 (13). Bioaccumulation in fish is increased in acid lakes.…”

Section: Zincmentioning

confidence: 99%

“…Speciation is not expected to be pH-dependent over the range pH 4-7. Mn has very low toxicity (13). Bioaccumulation in fish centra increases in acid lakes (22).…”

Section: Manganesementioning

confidence: 99%

“…The total concentration of Hg in water possibly increases as lakes acidify but this has not been verified experimentally. Speciation is theoretically strongly pHdependent over the range pH 4-7. Hg is highly toxic (13). Hg bioaccumulation in fish is increased in acid lakes.…”

Section: Mercurymentioning

confidence: 99%

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Effects of acidification on metal availability to aquatic biota, with special reference to filamentous algae.

Stokes¹,

Bailey²,

Groulx³

1985

Environ Health Perspect

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A survey of 34 shield lakes in Ontario and Quebec, pH 4.4 to 7.1, was made to evaluate which metals should be considered of concern as a risk to aquatic biota or consumers when lakes are acid stressed. A set of predictions, concerning the mobilization by man, the mobility, the chemical speciation, and the toxicity or bioaccumulation of metals in acid-stressed waters, were used as a basis for designing the study and organizing the results. Attached algae were used as biomonitors to assess metal bioavailability.The study concluded that zinc, lead, aluminum, and mercury were of concern in acid-stressed lakes, while the situation for manganese was unresolved, and cadmium was not studied. Nickel and copper were of concern only when a point source was involved. The study also concluded that the attached algal community had some value as a biomonitor, for metals in acid-stressed as well as metal-polluted surface waters.

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Correlation of physico-chemical parameters with toxicity of metal ions to plants

et al. 2000

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The in vivo toxicities of 12 metal ions to cabbage plants have been correlated with ion-speci®c physico-chemical parameters. Several regression models were statistically signi®cant but two different electronegativities in combination with Kaiser's electrochemical potential appeared to be the best determinants of metal ion toxicity, giving a good correlation (r 2 adjusted = 0.81 for 11 metal ions excluding copper, and 0.66 for all 12 metal ions). INTRODUCTIONThe study of the relationships between the physical or chemical structure of metal ions and their physiological actions began more than a century and a half ago. Since then many theories have been formulated for metal ion toxicity to vertebrate and invertebrate species and these continue to be developed. However, literature on similar relationships using plant material is still very limited, although there is an increasing need of structure-activity data in the expanding ®elds of ecotoxicology and phytotoxicology. Previous quantitative structure±activity relationship (QSAR) studies on metal ion toxicities have indicated that a variety of ion characteristics play a role in predicting the toxicity of metal ions. Biesinger and Christensen, 1 studying the toxic effects of metals on Daphnia magna Straus found correlations between the chronic toxicity of metals and the solubility of metal sul®des, electronegativity and the equilibrium constant of the metal±ATP complex. Various groups applied the theory of hard and soft acids and bases (HSAB theory) when investigating information on metal ion toxicity. Jones and Vaughn 2 obtained signi®cant correlations when plotting mouse and rat LD 50 data as a function of two softness parameters s p and s k , 3 and the results were con®rmed for mouse and Drosophila by Williams et al. 4 In addition, LD 50 values for acute toxicity of metal ions in mice were shown by Turner et al 5 to correlate better with the softness parameter, s p of Pearson and Mawby 6 than with many other physico-chemical characteristics of metal ions that were investigated. Kaiser, 7,8 using parameters derived from ionization potential and redox potential, developed a two-

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Correlation and Prediction of Metal Toxicity to Aquatic Biota

Cited by 84 publications

References 3 publications

Application of a Fish Dna Damage Assay as a Biological Toxicity Screening Tool for Metal Plating Wastewater

Application of a Fish Dna Damage Assay as a Biological Toxicity Screening Tool for Metal Plating Wastewater

Effects of acidification on metal availability to aquatic biota, with special reference to filamentous algae.

Correlation of physico-chemical parameters with toxicity of metal ions to plants

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