Correlation between cerebral tissue and central venous oxygen saturation during off-pump coronary bypass graft surgery

Abstract

We compared simultaneous regional cerebral oxygen saturation and central venous oxygen saturation at different time periods in 20 adult patients (median age, 57.9; range, 35 to 76 years) undergoing off-pump coronary artery bypass (OPCAB) graft surgery (n= 20). Mean arterial pressure (MAP), partial pressure of carbon dioxide (PcvCO(2)), heart rate, haematocrit (Hct), lactate and patient oxygen saturation (SpO(2)) were also recorded as a secondary analysis to determine independent predictors of cerebral desaturation and interactions between predictors. The cross-sectional analysis performed at each time point showed several significant moderate to strong positive correlations between central venous oxygen saturation and both right and left cerebral oxygen saturations; however, right cerebral saturations correlated better with central venous saturations than left cerebral saturation. Partial pressure of carbon dioxide (PcvCO(2)) was identified as a major predictor of cerebral saturation 0.59 (p < 0.001). Central venous saturation can be used as a surrogate measure of cerebral oxygen saturation during OPCAB surgery.

Preoperative mannitol infusion improves perioperative cerebral oxygen saturation and enhances postoperative recovery after laparoscopic cholecystectomy

“…Partial pressure of carbon dioxide (PaCO 2 ) was identified as a major predictor of cerebral saturation 24 since it was found to be the most potent physiologic cerebral vasodilator with the rate of cerebral blood flow increases linearly by 2-4% per mm Hg PaCO 2 within the range of 25-75 mm Hg. 25 , 26 There were no significant differences in our study between both groups in ETCO 2 since we maintained ETCO 2 within the normal range by mechanical ventilation.…”

A comparative study on regional cerebral oxygen saturation and central venous oxygen saturation as predictors of outcome in patients on off-pump coronary artery bypass graft surgery

“…The study further stated that with every one unit increase in left cerebral oxygen saturation, there was a corresponding 0.760 unit increase in ScvO 2 And with every one unit increase in right cerebral oxygen saturation, there was a corresponding 0.879 unit increase in ScvO 2 . 15 McQuillen et al, study on the association between regional and ScvO 2 in pediatric cardiac surgery concluded that neither individual values, nor changes in rSO2 are interchangeable measures of ScvO2 in postoperative pediatric cardiac patients. 16 Coronary artery disease is a disease of the adult population, and cardiac surgery in pediatric population was not considered in the current study.…”