Correlation between clinical parameters of periodontal disease and mean platelet volume in patients with coronary artery disease: a pilot study

Abstract

Chronic periodontitis in patients with CAD results in an increased MPV that may suggest increased platelet activity. This observation could indicate a potential pathophysiological link between chronic periodontitis and an increased risk of acute coronary syndromes.

Platelet indices (mean platelet volume and platelet distribution width) have correlations with periodontal inflamed surface area in coronary artery disease patients: A pilot study

“…In adolescents with mild periodontitis, a slight increase in MPV levels has been found . Higher MPV levels were found in previously diagnosed CAD patients with periodontitis compared to the control group, and significant correlations between clinical periodontal parameters (PD and CAL) and MPV were shown . A positive correlation between increased MPV and decreased PD after periodontal treatment in patients with severe periodontitis has also been shown …”

“…reported decreased MPV levels in severe periodontitis patients compared to the control group and showed that the MPV levels increased after periodontal therapy in this study group. Androsz‐Kowalska et al . reported that MPV was significantly higher in the patients with previously diagnosed CVD and coexisting chronic periodontitis than that in the control group, and correlations between clinical parameters of periodontal disease and MPV in patients with coronary artery disease were found.…”

Simple platelet markers: Mean platelet volume and congestive heart failure coexistent with periodontal disease. Pilot studies

“…Numerous papers have documented prognostic value of mean platelet volume (MPV) in cardiovascular pathology [1][2][3][4][5][6][7], including published research on correlation between MPV and periodontal disease (PDe) in coronary patients [8]. A thorough search on correlation between MPV and exacerbated heart failure revealed only 2 publications in this area [9,10].…”

How to predict the risk of postoperative complications after coronary artery bypass grafting in patients under 50 and over 80 years old. A retrospective cross-sectional study

“…Nevertheless, young patients with at least one risk factor for CAD should be closely monitored, and the prognostic value of non-cardiac conditions and gene polymorphism of the early onset and exacerbation of CAD is currently an active area of research [20,21].…”