Correlation between epicardial fat thickness and biochemical markers of metabolic risk

Rubio-Guerra, Alberto Francisco; Benítez-Maldonado, Daniel Rabindranath; Lozano-Nuevo, José Juan; Arana-Pazos, Karla C; Huerta-Ramírez, Saúl; Narváez-Rivera, Jorge Luis

doi:10.1016/j.medcle.2018.07.008

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…6 An EFT >3 mm has been associated with metabolic syndrome in the Mexican population. 7 The measurement of EFT on the free wall of the right ventricle, as described by Iacobellis et al, provides a simple, cheap and readily available assessment of EFT. 5,6 EFT has been associated with cardiovascular disease.…”

Section: Introductionmentioning

confidence: 99%

Correlation between epicardial fat thickness with intima–media thickness and ankle–brachial index in patients with metabolic syndrome

Arana-Pazos¹,

Narváez-Rivera²,

Maceda-Serrano³

et al. 2021

NMJI

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Background An increase in epicardial fat thickness (EFT) has been associated with increased cardiovascular risk and the development of atherosclerosis. Transthoracic echo-cardiography provides a reliable measurement of EFT. We evaluated the relationship of EFT with carotid intima–media thickness (CIMT) and ankle–brachial index (ABI), in patients with metabolic syndrome. Methods We assessed 80 patients with metabolic syndrome who underwent echocardiography; EFT was measured by two cardiologists. The CIMT (B-mode colour imaging of extracranial carotid arteries using high-resolution ultrasound) was also measured by a certified ultrasonographer, and ABI was measured by the main researcher. Results We did not find any correlation between ABI with EFT (r=0.0103, p=0.93) or with CIMT (r=–0.1625, p=0.15). However, we found a significant correlation between EFT and CIMT (r=0.2718, r2=0.074, p=0.015). When we evaluated the risk for a CIMT >0.9 mm in patients with an EFT >3 mm, we found a statistically significant association (p=0.039). Interestingly, only 1 patient with an EFT <3 mm had a CIMT >0.9 mm. Conclusion We found that the EFT correlates with CIMT in patients with metabolic syndrome, which explains, at least in part, the higher risk of atherosclerosis in them. Measurement of EFT should be part of the cardiovascular risk evaluation in patients with metabolic syndrome.

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